Fotograaf: Onbekend

dhr. prof. dr. ir. J.G.M. (Hans-Gerd) Janssen

  • Faculteit der Natuurwetenschappen, Wiskunde en Informatica
  • Bezoekadres
    Science Park A
    Science Park 904  Amsterdam
    Kamernummer: C2258B
  • Postadres:
    Postbus  94157
    1090 GD  Amsterdam
    T: 0205257610

Werkzaam bij Unilever, buitengewoon hoogleraar; bestuur Werkgroep Scheidingsmethoden KNCV.

Toepassing van Chrromatografie en Massaspectrometrie voor de karakterisering van grote moleculen en biologische systemen.



  • Pacheco Botelho Mourao, M., Kuijper, S., Dang, N. A., Walters, E., Janssen, H-G., & Kolk, A. H. J. (2016). Direct detection of Mycobacterium tuberculosis in sputum: A validation study using solid phase extraction-gas chromatography mass spectrometry. Journal of Chromatography B, 1012, 50-54. DOI: 10.1016/j.jchromb.2015.12.023 [details]
  • Lin, Y., Knol, D., Menéndez-Carreño, M., Blom, W. A. M., Matthee, J., Janssen, H. G., & Trautwein, E. A. (2016). Formation of Plant Sterol Oxidation Products in Foods during Baking and Cooking Using Margarine without and with Added Plant Sterol Esters. Journal of Agricultural and Food Chemistry, 64(3), 653-662. DOI: 10.1021/acs.jafc.5b04952 [details]
  • Wu, Y., Chen, G., Ji, C., Hoptroff, M., Jones, A., Collins, L. Z., & Janssen, H-G. (2016). Gas chromatography-mass spectrometry and Raman imaging measurement of squalene content and distribution in human hair. Analytical and Bioanalytical Chemistry, 408(9), 2357-2362. DOI: 10.1007/s00216-016-9335-0 [details]
  • du Chatinier, W., & Janssen, H-G. (2016). Combined chromatography and mass spectrometry for the molecular characterization of food emulsifiers. Journal of Chromatography A, 1439, 167-172. DOI: 10.1016/j.chroma.2016.01.019 [details]


  • Mourão, M. P. B., Denekamp, I., Kuijper, S., Kolk, A. H. J., & Janssen, H. G. (2015). Hyphenated and comprehensive liquid chromatography × gas chromatography-​mass spectrometry for the identification of Mycobacterium tuberculosis. Journal of Chromatography A, 1439, 152-160. DOI: 10.1016/j.chroma.2015.10.054 [details]
  • Chen, G., Miao, M., Hoptroff, M., Fei, X., Collins, L. Z., Jones, A., & Janssen, H. G. (2015). Sensitive and simultaneous quantification of zinc pyrithione and climbazole deposition from anti-dandruff shampoos onto human scalp. Journal of Chromatography B, 1003, 22-26. DOI: 10.1016/j.jchromb.2015.09.009 [details]
  • Dang, N. A., Mourão, M., Kuijper, S., Walters, E., Janssen, H-G., & Kolk, A. H. J. (2015). Direct detection of Mycobacterium tuberculosis in sputum using combined solid phase extraction-gas chromatography-mass spectrometry. Journal of Chromatography B, 986-987, 115-122. DOI: 10.1016/j.jchromb.2015.01.045 [details]
  • Menéndez-Carreño, M., Knol, D., & Janssen, H. G. (2015). Development and validation of methodologies for the quantification of phytosterols and phytosterol oxidation products in cooked and baked food products. Journal of Chromatography A, 1428, 316-325. DOI: 10.1016/j.chroma.2015.09.073 [details]


  • Barcaru, A., Anroedh-Sampat, A., Janssen, H-G., & Vivó-Truyols, G. (2014). Retention time prediction in temperature-​programmed, comprehensive two-​dimensional gas chromatography: Modeling and error assessment. Journal of Chromatography A, 1368, 190-198. DOI: 10.1016/j.chroma.2014.09.055 [details]
  • Bos, L. D. J., Martin-Loeches, I., Kastelijn, J. B., Gili, G., Espasa, M., Povoa, P., ... Schultz, M. J. (2014). The volatile metabolic fingerprint of ventilator-associated pneumonia. Intensive Care Medicine, 40(5), 761-762. DOI: 10.1007/s00134-014-3260-5 [details]
  • Chojnacka, A., Janssen, H-G., & Schoenmakers, P. (2014). Detailed study of polystyrene solubility using pyrolysis-gas chromatography-mass spectrometry and combination with size-exclusion chromatography. Analytical and Bioanalytical Chemistry, 406(2), 459-465. DOI: 10.1007/s00216-013-7461-5 [details]
  • Peroni, D., & Janssen, H-G. M. (2014). Comprehensive two-dimensional gas chromatography under high outlet pressure conditions: A new approach to correct the flow-mismatch issue in the two dimensions. Journal of Chromatography A, 1332, 57-63. DOI: 10.1016/j.chroma.2014.01.051 [details]


  • Dang, N. A., Kuijper, S., Walters, E., Claassens, M., van Soolingen, D., Vivo-Truyols, G., ... Kolk, A. H. J. (2013). Validation of Biomarkers for Distinguishing Mycobacterium tuberculosis from Non-Tuberculous Mycobacteria Using Gas Chromatography-Mass Spectrometry and Chemometrics. PLoS One, 8(10), e76263. DOI: 10.1371/journal.pone.0076263 [details] [PDF]
  • Dang, N. A., Kolk, A. H. J., Kuijper, S., Janssen, H-G., & Vivo-Truyols, G. (2013). The identification of biomarkers differentiating Mycobacterium tuberculosis and non-tuberculous mycobacteria via thermally assisted hydrolysis and methylation gas chromatography-mass spectrometry and chemometrics. Metabolomics, 9(6), 1274-1285. DOI: 10.1007/s11306-013-0531-z [details]
  • Peroni, D., Sampat, A. A. S., van Egmond, W., de Koning, S., Cochran, J., Lautamo, R., & Janssen, H-G. (2013). Comprehensive two-dimensional gas chromatography with a multi-capillary second dimension: A new column-set format for simultaneous optimum linear velocity operation. Journal of Chromatography A, 1317, 3-11. DOI: 10.1016/j.chroma.2013.07.097 [details]
  • Peters, S., Janssen, H-G., & Vivó-Truyols, G. (2013). A new method for the automated selection of the number of components for deconvolving overlapping chromatographic peaks. Analytica Chimica Acta, 799, 29-35. DOI: 10.1016/j.aca.2013.08.041 [details]
  • Chen, G., Hoptroff, M., Fei, X., Su, Y., & Janssen, H-G. (2013). Ultra-high-performance liquid chromatography-tandem mass spectrometry measurement of climbazole deposition from hair care products onto artificial skin and human scalp. Journal of Chromatography A, 1317, 155-158. DOI: 10.1016/j.chroma.2013.08.032 [details]
  • Poort, R., van Steenbergen, H., & Janssen, H-G. (2013). Detection and Identification of Natural Antioxidants in Edible Oils Using LC Fractionation with Off-Line Effect-Based Detection. LC GC North America, 31(3), 232-239. [details]
  • Poort, R., van Steenbergen, H., & Janssen, J. G. M. (2013). Detection and Identification of Natural Antioxidants in Edible Oil using LC Fractionation with Off-line Effect-Based Detection. LC GC Europe, 26(1), 232-239. [details]
  • van Steenbergen, H., Hrnčiřík, K., Ermacora, A., de Koning, S., & Janssen, H-G. (2013). Direct analysis of intact glycidyl fatty acid esters in edible oils using gas chromatography-mass spectrometry. Journal of Chromatography A, 1313, 202-211. DOI: 10.1016/j.chroma.2013.06.056 [details]


  • Bedani, F., Schoenmakers, P. J., & Janssen, H-G. (2012). Theories to support method development in comprehensive two-dimensional liquid chromatography - A review. Journal of Separation Science, 35(14), 1697-1711. DOI: 10.1002/jssc.201200070 [details]
  • Chojnacka, A., Kempe, K., van de Ven, H. C., Englert, C., Hoogenboom, R., Schubert, U. S., ... Schoenmakers, P. (2012). Molar mass, chemical-composition, and functionality-type distributions of poly(2-oxazoline)s revealed by a variety of separation techniques. Journal of Chromatography A, 1265, 123-132. DOI: 10.1016/j.chroma.2012.09.080 [details]
  • Peroni, D., Vanhoutte, D., Vilaplana, F., Schoenmakers, P., de Koning, S., & Janssen, H-G. (2012). Hydrophobic polymer monoliths as novel phase separators: Application in continuous liquid-liquid extraction systems. Analytica Chimica Acta, 720, 63-70. DOI: 10.1016/j.aca.2012.01.013 [details]
  • Peroni, D., van Egmond, W., Kok, W. T., & Janssen, J. G. M. (2012). Advancing liquid/liquid extraction through a novel microfluidic device: Theory, instrumentation and applications in gas chromatography. Journal of Chromatography A, 1226, 77-86. DOI: 10.1016/j.chroma.2011.08.001 [details]
  • Peroni, D., Vonk, R. J., van Egmond, W., & Janssen, H-G. (2012). Macroporous polymer monoliths as second dimension columns in comprehensive two-dimensional gas chromatography: a feasibility study. Journal of Chromatography A, 1268, 139-149. DOI: 10.1016/j.chroma.2012.10.019 [details]
  • Peters, S., Kaal, E., Horsting, I., & Janssen, H-G. (2012). An automated method for the analysis of phenolic acids in plasma based on ion-pairing micro-extraction coupled on-line to gas chromatography/mass spectrometry with in-liner derivatisation. Journal of Chromatography A, 1226, 71-76. DOI: 10.1016/j.chroma.2011.10.055 [details]
  • Menéndez-Carreño, M., Steenbergen, H., & Janssen, H-G. (2012). Development and validation of a comprehensive two-dimensional gas chromatography-mass spectrometry method for the analysis of phytosterol oxidation products in human plasma. Analytical and Bioanalytical Chemistry, 402(6), 2023-2032. DOI: 10.1007/s00216-011-5432-2 [details]


  • Chojnacka, A., Ghaffar, A., Feilden, A., Treacher, K., Janssen, H-G., & Schoenmakers, P. J. (2011). Pyrolysis-gas chromatography-mass spectrometry for studying N-vinyl-2-pyrrolidone-co-vinyl acetate copolymers and their dissolution behaviour. Analytica Chimica Acta, 706(2), 305-311. DOI: 10.1016/j.aca.2011.05.052 [details]
  • Peters, S., Janssen, H-G., & Vivó-Truyols, G. (2011). Untargeted metabolite discovery in kinetic data from multi-dose intervention studies. Journal of Chromatography A, 1218(21), 3337-3344. DOI: 10.1016/j.chroma.2010.11.023 [details]
  • Qureshi, R. N., Kaal, E., Janssen, H-G., Schoenmakers, P. J., & Kok, W. T. (2011). Determination of cholesterol and triglycerides in serum lipoproteins using flow field-flow fractionation coupled to gas chromatography-mass spectrometry. Analytica Chimica Acta, 706(2), 361-366. DOI: 10.1016/j.aca.2011.04.057 [details]
  • Fens, N., de Nijs, S. B., Peters, S., Dekker, T., Knobel, H. H., Vink, T. J., ... Sterk, P. J. (2011). Exhaled air molecular profiling in relation to inflammatory subtype and activity in COPD. The European Respiratory Journal, 38(6), 1301-1309. DOI: 10.1183/09031936.00032911 [details]
  • van Platerink, C. J., Janssen, H-G. M., Graf, B., Abrahamse, L., & Haverkamp, J. (2011). Quantification of steroid glycosides from Hoodia gordonii in porcine plasma using high performance liquid chromatography-mass spectrometry. Journal of Chromatography B, 879(11-12), 819-825. DOI: 10.1016/j.jchromb.2011.02.026 [details]


  • Brudin, S., Kaal, E., Janssen, H-G., & Schoenmakers, P. (2010). Evaluation of comprehensive on-line liquid chromatography thermally assisted hydrolysis and methylation-gas chromatography-mass spectrometry for characterization of sulfonated lignins. Journal of Separation Science, 33(22), 3604-3611. DOI: 10.1002/jssc.201000512 [details]
  • Peters, S., Janssen, H-G., & Vivó-Truyols, G. (2010). Trend analysis of time-series data: A novel method for untargeted metabolite discovery. Analytica Chimica Acta, 663(1), 98-104. DOI: 10.1016/j.aca.2010.01.038 [details]
  • Song, J., Grün, C. H., Heeren, R. M. A., Janssen, H-G., & van den Brink, O. F. (2010). High-resolution ion mobility spectrometry-mass spectrometry on poly(methyl methacrylate). Angewandte Chemie, International Edition, 49(52), 10168-10171. DOI: 10.1002/anie.201005225 [details]
  • Vivó-Truyols, G., & Janssen, H-G. (2010). Probability of failure of the watershed algorithm for peak detection in comprehensive two-dimensional chromatography. Journal of Chromatography A, 1217(8), 1375-1385. DOI: 10.1016/j.chroma.2009.12.063 [details]


  • Bedani, F., & Janssen, H-G. (2009). Using two-dimensional liquid chromatography to separate complex mixtures of peptides. LC GC Europe, 22(5), 248-255. [details]
  • Bedani, F., Kok, W. T., & Janssen, H-G. (2009). Optimal gradient operation in comprehensive liquid chromatography × liquid chromatography systems with limited orthogonality. Analytica Chimica Acta, 654(1), 77-84. DOI: 10.1016/j.aca.2009.06.042 [details]
  • Janssen, H-G., Kaal, E., & de Koning, S. (2009). Comprehensive multidimensional systems incorporating GC×GC. In L. Ramos (Ed.), Comprehensive two dimensional gas chromatography. (pp. 123-145). (Wilson & Wilson's comprehensive analytical chemistry; No. 55). Amsterdam: Elsevier. DOI: 10.1016/S0166-526X(09)05506-8 [details]
  • Kaal, E., Kolk, A. H. J., Kuijper, S., & Janssen, H-G. (2009). A fast method for the identification of Mycobacterium tuberculosis in sputum and cultures based on thermally assisted hydrolysis and methylation followed by gas chromatography-mass spectrometry. Journal of Chromatography A, 1216(35), 6319-6325. DOI: 10.1016/j.chroma.2009.06.078 [details]
  • Peters, S., van Velzen, E., & Janssen, H-G. (2009). Parameter selection for peak alignment in chromatographic sample profiling: Objective quality indicators and use of control samples. Analytical and Bioanalytical Chemistry, 394(5), 1273-1281. DOI: 10.1007/s00216-009-2662-7 [details] [PDF]
  • Visser, I., Klinkenberg, M., Hoos, P., Janssen, H-G., & van Duynhoven, J. (2009). Identification and quantification of polycarboxylates in detergent products using off-line size exclusion chromatography-nuclear magnetic resonance. Analytica Chimica Acta, 654(1), 40-44. DOI: 10.1016/j.aca.2009.06.017 [details]
  • Zhang, Q., van der Klift, E. J. C., Janssen, H-G., & van Beek, T. A. (2009). An on-line normal-phase high performance liquid chromatography method for the rapid detection of radical scavengers in non-polar food matrixes. Journal of Chromatography A, 1216(43), 7268-7274. DOI: 10.1016/j.chroma.2009.08.043 [details]
  • de Koning, S., Janssen, H-G., & Brinkman, U. A. T. (2009). Modern methods of sample preparation for GC analysis. Chromatographia, 69(S1), S33-S78. DOI: 10.1365/s10337-008-0937-3 [details] [PDF]


  • Grün, C. H., van Dorsten, F. A., Jacobs, D. M., Le Belleguic, M., van Velzen, E. J. J., Bingham, M. O., ... van Duynhoven, J. P. M. (2008). GC-MS methods for metabolic profiling of microbial fermentation products of dietary polyphenols in human and in vitro intervention studies. Journal of Chromatography B, 871(2), 212-219. DOI: 10.1016/j.jchromb.2008.04.039 [details]
  • Janssen, H-G., Swindells, C., Gunning, P., Wang, W., Grün, C., Mahabir, K., ... Apps, P. J. (2008). Quantification of appetite suppressing steroid glycosides from Hoodia gordonii in dried plant material, purified extracts and food products using HPLC-UV and HPLC-MS methods. Analytica Chimica Acta, 617(1-2), 200-207. DOI: 10.1016/j.aca.2008.01.022 [details]
  • Kaal, E. R., Kurano, M., Geissler, M., & Janssen, H-G. (2008). Hyphenation of aqueous liquid chromatography to pyrolysis-gas chromatography and mass spectrometry for the comprehensive characterization of water-soluble polymers. Journal of Chromatography A, 1186(1-2), 222-227. DOI: 10.1016/j.chroma.2007.10.035 [details]
  • Kaal, E., de Koning, S., Brudin, S., & Janssen, H-G. (2008). Fully automated system for the gas chromatographic characterization of polar biopolymers based on thermally assisted hydrolysis and methylation. Journal of Chromatography A, 1201(2), 169-175. DOI: 10.1016/j.chroma.2008.05.047 [details]
  • Kaal, E., & Janssen, H-G. (2008). Extending the molecular application range of gas chromatography. Journal of Chromatography A, 1184(1-2), 43-60. DOI: 10.1016/j.chroma.2007.11.114 [details]
  • Grandpierre, C., Janssen, H-G., Laroche, C., Michaud, P., & Warrand, J. (2008). Enzymatic and chemical degradation of curdlan targeting the production of β-(1 → 3) oligoglucans. Carbohydrate polymers, 71(2), 277-286. DOI: 10.1016/j.carbpol.2007.05.042 [details]
  • de Koning, S., Kaal, E., Janssen, H-G., van Platerink, C., & Brinkman, U. A. T. (2008). Characterization of olive oil volatiles by multi-step direct thermal desorption-comprehensive gas chromatography-time-of-flight mass spectrometry using a programmed temperature vaporizing injector. Journal of Chromatography A, 1186(1-2), 228-235. DOI: 10.1016/j.chroma.2007.05.066 [details]
  • van Platerink, C. J., Janssen, H-G. M., & Haverkamp, J. (2008). Application of at-line two-dimensional liquid chromatography-mass spectrometry for identification of small hydrophilic angiotensin I-inhibiting peptides in milk hydrolysates. Analytical and Bioanalytical Chemistry, 391(1), 299-307. DOI: 10.1007/s00216-008-1990-3 [details] [PDF]


This list of publications is extracted from the UvA-Current Research Information System. Questions? Ask the library or the Pure staff of your faculty / institute. Log in to Pure to edit your publications.
  • Unilever Research Vlaardingen
    Scientist and groep-leader Analytical Chemistry

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