prof. dr. T.W.J. (Dorus) Gadella

List

Faculty of Science
SILS
POSTBUS 94215
1090 GE Amsterdam
Room number: C2.266
Th.W.J.Gadella@uva.nl
T: 0205256259

Publications
Ancillary activities

refereed(34)
academic(1)

2014

E. Hoogendoorn, K.C. Crosby, D. Leyton-Puig, R.M.P. Breedijk, K. Jalink, Th.W.J. Gadella & M. Postma (2014). The fidelity of stochastic single-molecule super-resolution reconstructions critically depends upon robust background estimation. Scientific Reports, 4, 3854. doi: 10.1038/srep03854[go to publisher's site]
D.S. Bindels, J. Goedhart, M.A. Hink, L. van Weeren, L. Joosen & T.W.J. Gadella (jr.) (2014). Optimization of fluorescent proteins. In Y. Engelborghs & A.J.W.G. Visser (Eds.), Fluorescence Spectroscopy and Microscopy: Methods and Protocols (Methods in Molecular Biology, 1076) (pp. 371-417). New York: Humana Press.
L. Joosen, M.A. Hink, T.W.J. Gadella & J. Goedhart (2014). Effect of fixation procedures on the fluorescence lifetimes of Aequorea victoria derived fluorescent proteins. Journal of Microscopy, 256 (3), 166-176. doi: 10.1111/jmi.12168
S. Moling, A. Pietraszewska-Bogiel, M. Postma, E. Fedorova, M.A. Hink, E. Limpens, T.W. Gadella & T. Bisseling (2014). Nod factor receptors form heteromeric complexes and are essential for intracellular infection in medicago nodules. The Plant Cell, 26 (10), 4188-99. doi: 10.1105/tpc.114.129502

2013

K.C. Crosby, M. Postma, M.A. Hink, C.H.C. Zeelenberg, M.J.W. Adjobo-Hermans & T.W.J. Gadella (2013). Quantitative analysis of self-association and mobility of annexin A4 at the plasma membrane. Biophysical Journal, 104 (9), 1875-1885. doi: 10.1016/j.bpj.2013.02.057[go to publisher's site]
J. Goedhart, J. van Unen, M.J.W. Adjobo-Hermans & T.W.J. Gadella (jr.) (2013). Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular location. Scientific Reports, 3, 2284. doi: 10.1038/srep02284[go to publisher's site]
M.J.W. Adjobo-Hermans, K.C. Crosby, M. Putyrski, A. Bhageloe, L. van Weeren, C. Schultz, J. Goedhart & T.W.J. Gadella (jr.) (2013). PLCbeta isoforms differ in their subcellular location and their CT-domain dependent interaction with Galphaq. Cellular Signalling, 25 (1), 255-263. doi: 10.1016/j.cellsig.2012.09.022
D.S. Bilan, L. Pase, L. Joosen, A.Y. Gorokhovatsky, Y.G. Ermakova, T.W.J. Gadella, C. Grabher, C. Schultz, S. Lukyanov & V.V. Belousov (2013). HyPer-3: A Genetically Encoded H(2)O(2) Probe with Improved Performance for Ratiometric and Fluorescence Lifetime Imaging. ACS Chemical Biology, 8 (3), 535-542. doi: 10.1021/cb300625g[go to publisher's site]
A. Pietraszewska-Bogiel, B. Lefebvre, A.M. Koini, D. Klaus-Heisen, F.L.W. Takken, R. Geurts, J.V. Cullimore & Th.W.J. Gadella (2013). Interaction of Medicago truncatula Lysin Motif Receptor-Like Kinases, NFP and LYK3, Produced in Nicotiana benthamiana Induces Defence-Like Responses. PLoS One, 8 (6), e65055. doi: 10.1371/journal.pone.0065055[go to publisher's site]

2012

J. Goedhart, D. von Stetten, M. Noirclerc-Savoye, M. Lelimousin, L. Joosen, M.A. Hink, L. van Weeren, Th.W.J. Gadella & A. Royant (2012). Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%. Nature Communications, 3, 751. doi: 10.1038/ncomms1738
D. von Stetten, M. Noirclerc-Savoye, J. Goedhart, T.W.J. Gadella & A. Royant (2012). Structure of a fluorescent protein from Aequorea victoria bearing the obligate-monomer mutation A206K. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68 (Pt 8), 878-882. doi: 10.1107/S1744309112028667[go to publisher's site]
D.M. Shcherbakova, M.A. Hink, L. Joosen, Th.W.J. Gadella & V.V. Verkhusha (2012). An orange fluorescent protein with a large Stokes shift for single-excitation multicolor FCCS and FRET imaging. Journal of the American Chemical Society, 134 (18), 7913-7923. doi: 10.1021/ja3018972

2011

K.C. Crosby, A. Pietraszewska-Bogiel, T.W.J. Gadella (jr.) & B.S.J. Winkel (2011). Förster resonance energy transfer demonstrates a flavonoid metabolon in living plant cells that displays competitive interactions between enzymes. FEBS Letters, 585 (14), 2193-2198. doi: 10.1016/j.febslet.2011.05.066
M.J.W. Adjobo-Hermans, J. Goedhart, L. van Weeren, S. Nijmeijer, E.M.M. Manders, S. Offermanns & T.W.J. Gadella (jr.) (2011). Real-time visualization of heterotrimeric G protein Gq activation in living cells. BMC Biology, 9, 32. doi: 10.1186/1741-7007-9-32[go to publisher's site]
D. Klaus-Heisen, A. Nurisso, A. Pietraszewska, M. Mbengue, S. Camut, T. Timmers, C. Pichereaux, M. Rossignol, T.W.J. Gadella, A. Imberty, B. Lefebvre & J.V. Cullimore (2011). Structure-function similarities between a plant receptor-like kinase and the human interleukin-1 receptor-associated kinase-4. The Journal of Biological Chemistry, 286 (13), 11202-11210.
J. Goedhart, L. van Weeren, M.J.W. Adjobo-Hermans, I. Elzenaar, M.A. Hink & T.W.J. Gadella (jr.) (2011). Quantitative co-expression of proteins at the single cell level - application to a multimeric FRET sensor. PLoS One, 6 (11). doi: 10.1371/journal.pone.0027321.t001[go to publisher's site]
J. Goedhart & T.W.J. Gadella (jr.) (2011). Bypassing GPCRs with chemical dimerizers. Chemistry & Biology, 18 (9), 1067-1068. doi: 10.1016/j.chembiol.2011.09.004
A. Pietraszewska-Bogiel & T.W.J. Gadella (2011). FRET microscopy: from principle to routine technology in cell biology. Journal of Microscopy, 241 (2), 111-118. doi: 10.1111/j.1365-2818.2010.03437.x
J.B. Klarenbeek, J. Goedhart, M.A. Hink, T.W.J. Gadella & K. Jalink (2011). A mTurquoise-based cAMP sensor for both FLIM and ratiometric read-out has improved dynamic range. PLoS One, 6 (4), e19170. doi: 10.1371/journal.pone.0019170[go to publisher's site]

2010

C. Schultz, A.B. Neef, T.W.J. Gadella (jr.) & J. Goedhart (2010). Labeling lipids for imaging fixed cells. Cold Spring Harbor protocols, 8, pdb.prot5458. doi: 10.1101/pdb.prot5458
C. Schultz, A.B. Neef, T.W.J. Gadella (jr.) & J. Goedhart (2010). Labeling lipids for imaging in live cells. Cold Spring Harbor protocols, 8, pdb.prot5459. doi: 10.1101/pdb.prot5459
J. Goedhart, L. van Weeren, M.A. Hink, N.O.E. Vischer, K. Jalink & T.W.J. Gadella (jr.) (2010). Bright cyan fluorescent protein variants identified by fluorescence lifetime screening. Nature Methods, 7 (2), 137-139. doi: 10.1038/nmeth.1415
S. Alexeeva, T.W.J. Gadella (jr.), J. Verheul, G.S. Verhoeven & T. den Blaauwen (2010). Direct interactions of early and late assembling division proteins in Escherichia coli cells resolved by FRET. Molecular Microbiology, 77 (2), 384-398. doi: 10.1111/j.1365-2958.2010.07211.x
C. Schultz, A.B. Neef, T.W.J. Gadella (jr.) & J. Goedhart (2010). Imaging lipids in living cells. Cold Spring Harbor protocols, 8, pdb.top83. doi: 10.1101/pdb.top83
F.V. Subach, L. Zhang, T.W.J. Gadella, N.G. Gurskaya, K.A. Lukyanov & V.V. Verkhusha (2010). Red fluorescent protein with reversibly photoswitchable absorbance for photochromic FRET. Chemistry & Biology, 17 (7), 745-755. doi: 10.1016/j.chembiol.2010.05.022
C. Schultz, A.B. Neef, T.W.J. Gadella (jr.) & J. Goedhart (2010). Transfection of cells with DNA encoding a visible fluorescent protein-tagged lipid-binding domain. Cold Spring Harbor protocols, 8, pdb.prot5457. doi: 10.1101/pdb.prot5457

2009

D. Shcherbo, E.A. Souslova, J. Goedhart, T.V. Chepurnykh, A. Gaintzeva, I.I. Shemiakina, T.W.J. Gadella, S. Lukyanov & D.M. Chudakov (2009). Practical and reliable FRET/FLIM pair of fluorescent proteins. BMC Biotechnology, 9, 24.[go to publisher's site]
J.E.M. Vermeer, J.M. Thole, J. Goedhart, E. Nielsen, T. Munnik & T.W.J. Gadella (jr.) (2009). Imaging phosphatidylinositol 4-phosphate dynamics in living plant cells. Plant Journal, 57 (2), 356-372.

2008

J. Rino, J.M.P. Desterro, T.R. Pacheco, T.W.J. Gadella (jr.) & M. Carmo-Fonseca (2008). Splicing factors SF1 and U2AF associate in extraspliceosomal complexes. Molecular and Cellular Biology, 28 (9), 3045-3057.
M. Schenning, J. Goedhart, T.W.J. Gadella (jr.), D. Avram, K.W.A. Wirtz & G.T. Snoek (2008). The anti-apoptotic activity associated with phosphatidylinositol transfer protein α activates the MAPK and Akt/PKB pathway. Biochimica et Biophysica Acta-Molecular Cell Research, 1783 (10), 1700-1706.
M.J.W. Adjobo-Hermans, J. Goedhart & Th.W.J. Gadella (2008). Regulation of PLCβ1a membrane anchoring by its substrate phosphatidylinositol (4,5)-bisphosphate. Journal of Cell Science, 121 (22), 3770-3777.
G.J. Kremers, E.B. van Munster, J. Goedhart & Th.W.J. Gadella (2008). Quantitative lifetime unmixing of multiexponentially decaying fluorophores using single-frequency fluorescence lifetime imaging microscopy. Biophysical Journal, 95 (1), 378-389.[go to publisher's site]
P. Dhonukshe, I. Grigoriev, R. Fischer, M. Tominaga, D.G. Robinson, J. Hašek, T. Paciorek, J. Petrášek, D. Seifertová, R. Tejos, L.A. Meisel, E. Zažímalová, T.W.J. Gadella (jr.), Y.-D. Stierhof, T. Ueda, K. Oiwa, A. Akhmanova, R. Brock, A. Spang & J. Friml (2008). Auxin transport inhibitors impair vesicle motility and actin cytoskeleton dynamics in diverse eukaryotes. Proceedings of the National Academy of Sciences of the United States of America, 105 (11), 4489-4494.
J.M. Thole, J.E.M. Vermeer, Y. Zhang, Th.W.J. Gadella & E. Nielsen (2008). Root hair defective4 encodes a phosphatidylinositol-4-phosphate phosphatase required for proper root hair development in Arabidopsis thaliana. The Plant Cell, 20 (2), 381-395.

2009

J. Goedhart & T.W.J. Gadella (jr.) (2009). Fluorescence resonance energy transfer imaging of PKC signalling in living cells using genetically encoded fluorescent probes. Journal of the Royal Society Interface, 6 (S1), S27-S34.[go to publisher's site]

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Van Leeuwenhoek Centre Adv. Microscopy
Directeur
Euro-BioImaging Interim Board
Member

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