5-HT3 receptor-mediated signaling 

 

Publications:

 

Murthy, S., Niquille, M., Hurni, N., Limoni, G., Frazer, S., Chameau, P., van Hooft, J.A., Vitalis, T., and Dayer, A. 

Serotonin receptor 3A controls interneuron migration into the neocortex.

Nature Communications 5, 5524 (2014). 

 

Oostland, M., Buijink, M.R., Teunisse, G.M., von Oerthel, L., Smidt, M.P. and van Hooft, J.A.

Distinct temporal expression of 5-HT_1A and 5-HT_2A receptors on cerebellar granule cells in mice

Cerebellum, 13, 491-500 (2014).

 

Oostland, M. and van Hooft, J.A.

The role of serotonin in cerebellar development

Neuroscience, 248, 201-212 (2013).

 

Smidt, M.P. and van Hooft, J.A.

Subset specification of central serotonergic neurons

Frontiers in Cellular Neuroscience, 7, 200 (2013).

 

Engel, M., Smidt, M.P. and van Hooft, J.A.

The serotonin 5-HT₃ receptor: a novel neurodevelopmental target

Frontiers in Cellular Neuroscience, 7, 76 (2013).

 

Oostland, M., Buijink, M.R. and van Hooft, J.A.

Serotonergic control of Purkinje cell maturation and climbing fibre elimination by 5-HT₃ receptors in the juvenile mouse cerebellum

Journal of Physiology, 591, 1793-1807 (2013).

 

van der Velden, L., van Hooft, J.A.* and Chameau, P.*

Altered dendritic complexity affects firing properties of cortical layer 2/3 pyramidal neurons in mice lacking the 5-HT_3A receptor.

Journal of Neurophysiology, 108, 1521-1528 (2012).

* shared last authorship

 

Smit-Rigter, L.A., Noorlander, C.W., von Oerthel, L., Chameau, P., Smidt, M.P. and van Hooft, J.A.

Prenatal fluoxetine exposure induces life-long serotonin 5-HT₃ receptor-dependent cortical abnormalities and anxiety-like behaviour.

Neuropharmacology, 62, 865-870 (2012).

 

Smit-Rigter, L.A., Wadman, W.J. and van Hooft, J.A.

Alterations in apical dendrite bundling in the somatosensory cortex of 5-HT_3A receptor knockout mice

Frontiers in Neuroanatomy, 5, 64 (2011).

 

Oostland, M., Sellmeijer, J. and van Hooft, J.A.

Transient expression of functional serotonin 5-HT₃ receptors by glutamatergic granule cells in the early postnatal mouse cerebellum.

Journal of Physiology, 589, 4837-4846 (2011).

 

Smit-Rigter, L.A., Wadman, W.J. and van Hooft, J.A.

Impaired social behavior in 5-HT_3A receptor knockout mice.

Frontiers in Behavioral Neuroscience, 4, 169 (2010).

 

Vucurovic, K., Gallopin, T., Ferezou, I., Rancillac, A., Chameau, P., van Hooft, J.A., Monyer, H., Rossier, J. and Vitalis, T.

Serotonin 3A receptor subtype as an early and protracted marker of cortical interneurons subpopulations.

Cerebral Cortex, 20, 2333-2347 (2010).

 

Smit-Rigter, L.A., Champagne, D.L. and van Hooft, J.A.

Lifelong impact of variations in maternal care on dendritic structure and function of cortical layer 2/3 pyramidal neurons in rat offspring.

PLoS ONE, 4, e5167 (2009).

 

Chameau, P., Inta, D., Vitalis, T., Monyer, H., Wadman, W.J. and van Hooft, J.A.

The N-terminal fragment of reelin controls postnatal dendritic maturation of cortical pyramidal neurons.

Proceedings of the National Academy of Sciences U.S.A., 106, 7227-7232 (2009).

 

Inta, D., Alfonso, J., von Engelhardt, J., Kreuzberg, M., Meyer, A.H., van Hooft, J.A. and Monyer, H.

Neurogenesis and widespread forebrain migration of distinct GABAergic neurons from the postnatal subventricular zone.

Proceedings of the National Academy of Sciences U.S.A., 105, 20994-20999 (2008).

 

Noam, Y., Wadman, W.J. and van Hooft, J.A.

On the voltage-dependent Ca²⁺ block of serotonin 5-HT₃ receptors: a critical role of intracellular phosphates.

Journal of Physiology, 586, 3629-3638 (2008).

 

Chameau, P. and van Hooft, J.A.

Serotonin 5-HT₃ receptors in the central nervous system.

Cell & Tissue Research, 326, 573-581 (2006).

 

van Welie, I., Remme, M.W.H., van Hooft, J.A. and Wadman, W.J.

Different levels of I_h determine distinct temporal integration in bursting and regular-spiking neurons in rat subiculum.

Journal of Physiology, 576, 203-214 (2006).

 

van Welie, I., van Hooft, J.A. and Wadman, W.J.

Background activity regulates excitability of rat hippocampal CA1 pyramidal neurons by adaptation of a K⁺ conductance.

Journal of Neurophysiology, 95, 2007-2012 (2006).

 

van Welie, I., Wadman, W.J. and van Hooft, J.A.

Low affinity block of native and cloned hyperpolarization-activated I_h channels by Ba²⁺ ions.

European Journal of Pharmacology, 507, 15-20 (2005).

 

van Welie, I., van Hooft, J.A. and Wadman, W.J.

Homeostatic scaling of neuronal excitability by synaptic modulation of somatic hyperpolarization-activated I_h channels.

Proceedings of the National Academy of Sciences U.S.A., 101, 5123-5128 (2004).

 

van Hooft, J.A. and Yakel, J.L.

5-HT₃ receptors in the CNS: 3b or not 3b?

Trends in Pharmacological Sciences, 24, 157-160 (2003).

 

van Hooft, J.A. and Wadman, W.J.

Ca²⁺ ions block and permeate serotonin 5-HT₃ receptor channels in rat hippocampal interneurons.

Journal of Neurophysiology, 89, 1864-1869 (2003).

 

Sudweeks, S.N., van Hooft, J.A. and Yakel, J.L.

Serotonin 5-HT₃ receptors in rat CA1 hippocampal interneurons: functional and molecular characterization.

Journal of Physiology, 544, 715-726 (2002).

 

van Hooft, J.A., Dougherty, J.J., Endeman, D., Nichols, R.A. and Wadman, W.J.

Gabapentin inhibits presynaptic Ca²⁺ influx and synaptic transmission in rat hippocampus and neocortex.

European Journal of Pharmacology, 449, 221-228 (2002).

 

van Hooft, J.A.

Fast Green FCF (Food Green 3) inhibts synaptic activity in rat hippocampal interneurons.

Neuroscience Letters, 318, 163-165 (2002).

 

van Hooft, J.A. and Vijverberg, H.P.M.

5-HT₃ receptors and neurotransmitter release in the CNS: a nerve ending story?

Trends in Neurosciences, 23, 605-610 (2000).

 

van Hooft, J.A., Giuffrida, R., Blatow, M. and Monyer, H.

Differential expression of group I metabotropic glutamate receptors in functionally distinct hippocampal interneurons.

Journal of Neuroscience, 20, 3544-3551 (2000).

 

Giffard, R.G., Papadopoulos, M.C., van Hooft, J.A., Xu, L., Giuffrida, R. and Monyer, H.

The electrogenic sodium bicarbonate cotransporter: developmental expression in rat brain and possible role in acid vunerability.

Journal of Neuroscience, 20, 1001-1008 (2000).

 

van Hooft, J.A., Spier, A.D., Yakel, J.L., Lummis, S.C.R. and Vijverberg, H.P.M.

Promiscuous coassembly of serotonin 5-HT₃ and nicotinic a4 receptor subunits into Ca²⁺ permeable ion channels.

Proceedings of the National Academy of Sciences U.S.A., 95, 11456-11461 (1998).

 

van Hooft, J.A. and Vijverberg, H.P.M.

Agonist and antagonist effects of apomorphine enantiomers on 5-HT₃ receptors.

Neuropharmacology, 37, 259-264 (1998).

 

Zwart, R., van Kleef, R.G.D.M., van Hooft, J.A., Oortgiesen, M. and Vijverberg, H.P.M.

Cellular aspects of persistent neurotoxicants: effects of Pb²⁺ on neuronal nicotinic acetylcholine receptors.

Neurotoxicology 18, 709-718 (1997).

 

van Hooft, J.A., Kreikamp, A.P. and Vijverberg, H.P.M.

Native 5-HT₃ receptors expressed in Xenopus oocytes differ from homopentameric 5-HT₃ receptors.

Journal of Neurochemistry 69, 1318-1321 (1997).

 

van Hooft, J.A., van der Haar, E. and Vijverberg, H.P.M.

Allosteric potentiation of the 5-HT₃ receptor-mediated ion current in N1E-115 neuroblastoma cells by 5-hydroxyindole and analogues.

Neuropharmacology 36, 649-653 (1997).

 

van Hooft, J.A. and Vijverberg, H.P.M.

RS-056812-198: partial agonist on native and antagonist on cloned 5-HT₃ receptors.

European Journal of Pharmacology 322, 229-233 (1997).

 

van Hooft, J.A. and Vijverberg, H.P.M.

Full and partial agonists induce distinct desensitized states of the 5-HT₃ receptor.

Journal of Receptor and Signal Transduction Research 17, 267-277 (1997).

 

van Hooft, J.A. and Vijverberg , H.P.M.

Selection of distinct conformational states of the 5-HT₃ receptor by full and partial agonists.

British Journal of Pharmacology 117, 839-846 (1996).

 

van Hooft, J.A. and Vijverberg, H.P.M.

Phosphorylation controls conductance of 5-HT₃ receptor ligand-gated ion channels.

Receptors & Channels 3, 7-12 (1995).

 

Kooyman, A.R., Zwart, R., Vanderheijden, P.M.L., van Hooft, J.A. and Vijverberg, H.P.M.

Interaction between enantiomers of mianserin and ORG3770 at 5-HT₃ receptors in cultured mouse neuroblastoma cells.

Neuropharmacology 33, 501-507 (1994).

 

Kooyman, A.R., van Hooft, J.A., Vanderheijden, P.M.L. and Vijverberg, H.P.M.

Competetive and non-competetive effects of 5-hydroxyindole on 5-HT₃ receptors in N1E-115 neuroblastoma cells.

British Journal of Pharmacology 112, 541-546 (1994).

 

van Hooft, J.A., Kooyman, A.R., Verkerk, A., van Kleef, R.G.D.M. and Vijverberg, H.P.M.

Single 5-HT₃ receptor-gated ion channel events resolved in N1E-115 mouse neuroblastoma cells.

Biochemical and Biophysical Research Communications 199, 227-233 (1994).

 

Kooyman, A.R., van Hooft, J.A. and Vijverberg, H.P.M.

5-Hydroxyindole slows desensitization of the serotonin 5-HT₃ receptor-mediated ion current in N1E-115 neuroblastoma cells.

British Journal of Pharmacology 108, 287-289 (1993).

 

 

 

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