IGG-FC-glycosylation of antibodies
Myrthe Sonneveld researched antibody Fc-glycosylation affecting alloimmunity and autoimmunity towards blood cells in order to help develop new diagnostic methods to predict the severity of alloantibody-derived blood disease. Examples include fetal or newborn haemolytic disease, better known as Rhesus disease, and fetal or neonatal alloimmune thrombocytopenia. In addition, Sonneveld looked at the Fc-glycosylation of autoantibody-derived blood diseases, attempting to understand why the immune system makes B cells to produce differently glycosylated antibodies.
M.E. Sonneveld: IgG-Fc-Glycosylation in Immune-Mediated Cytopenias.
Prof. C.E. van der Schoot and Prof. M. Wuhrer (Universiteit Leiden)
Dr G. Vidarsson (Sanquin Research)
T his event is open to the public.
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