Lipotoxicity in adrenoleukodystrophy

Medicine

PhD defence ceremony

X-linked adrenoleukodystrophy (ALD) is a peroxisomal metabolic disorder with a birth incidence of one in 14,700. All patients have a mutation n the gene ABCD1 that encodes a perixisomal transmembrane protein that transports very long-chain fatty acids into the peroxisome. As a result, these acids accumulate in plasma and the cells o all tissues. The aim of Malu-Clair van de Beek's research is to improve the diagnosis of ALD.

M. van de Beek: Lipotoxicity in Adrenoleukodystrophy. Size Matters! 

Supervisors

Prof. R.J.A. Wanders

Prof. F.A. Wijburg

Co-supervisors

Dr S. Kemp

Prof. B.T. Poll-The

Entrance

This event is open to the public.

Published by  University of Amsterdam