dhr. prof. dr. M.W.M. (Michiel) van den Brekel
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Faculteit der Geesteswetenschappen
Capaciteitsgroep Taalwetenschap
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Spuistraat
210
1012 VT Amsterdam
Kamernummer: 312
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M.W.M.vandenBrekel@uva.nl
Interview
Not only is Michiel van den Brekel professor at the Faculty of Humanities, he is also head of the department of Head and Neck Oncology and Surgery at the Netherlands Cancer Institute and a staff member in the department of Otorhinolaryngology at the Amsterdam Academic Medical Centre. Appointed as Professor of Oncology-Related Voice and Speech Disorders in 2011, Van den Brekel is excited about the prospect of helping to further the cooperative relationship between the humanities and medicine. A fertile ground for cooperation The idea that a university chair with the medical name 'oncology related voice and speech disorders' could form part of a humanities faculty seems counterintuitive, if not downright absurd. Indeed, thinking of medicine and humanities, one is easily excused for viewing these two disciplines as polar opposites, with little or nothing in common. And yet, on closer inspection, the links between them are as strong as they are beneficial; something to which Van den Brekel's own chair attests. Said Van den Brekel: 'Within the ACLC (Amsterdam Center for Language and Communication) there is substantial knowledge about speech, articulation and language, which can be practically applied within head and neck oncology. One of the goals of the research group is to ascertain whether patients can compensate for changes in voice and speech, and if yes, in what way? The ACLC plays a pivotal role in the linguistic side of the rehabilitation process. With the help of speech technology, our aim is to get a more comprehensive insight into the possible consequences an operation might have on a patient, so that we are able to provide better counseling about the various treatment options that are available.' Linking the fields of humanities and medicine One of Van den Brekel's research fields is oncology related voice and speech disorders, which is a subject area in which the Faculty of Humanities provides unique expertise. Head and neck cancer is the sixth most common type of cancer in the Netherlands, with approximately 3000 patients treated for this disease annually. Van den Brekel: "Many patients with a tumor in their larynx and throat end up with impairments in speech and have difficulty swallowing partly as a result of the treatment. The research into these impairments can be done from both a medical and academic perspective.' To illustrate the unique role that the humanities can play in oncology, Van den Brekel mentions a research project currently being carried out by one of the Faculty's PhD candidates, whereby speech technology is used for exploring a patient's comprehensibility and quality of voice after oncological treatment. As yet, patients suffering from voice and speech impairment after an operation usually visit a speech therapist, who then gives them exercises to do. In most cases both speech therapist and patient usually believe they're able to detect improvements after a few months of exercise, which is by no means an objective assumption. In this sense speech therapy is still a relatively young science. It would therefore be advantageous to use voice recognition software that automatically measures such things as speech quality, comprehension and all sorts of aspects surrounding articulation. In using such a device, both patient and speech therapist would be better informed about the current stage of rehabilitation and what still needs to be done. This is a process in which linguistic knowledge and techniques can play a major role. A stimulating environment It is now almost a year since Van den Brekel started working at the Faculty of Humanities, which begs the question: does he feel like a humanities scholar? 'Although I'm a physician above all, I do enjoy working at the Faculty. As a medical practitioner you're mostly confined to a hospital. It's therefore really refreshing to see people at this Faculty engaged in totally different things. My own chair forms a beneficial link between the Faculty of Humanities and the medical world
2015
- S.A.C. Kraaijenga, M.W.M. van den Brekel, L.E. Smeele & O. Lapid (2015). Herstel van slik- en stemfunctie met behulp van lipofilling in de mond- of keelholte na behandeling voor hoofd- halskanker. NED TIJDSCHR PLAST CHIR, 2015 (1), 31-36.
2014
- C. van den Boer, J.H. Vas Nunes, S.H. Muller, V. van der Noort, M.W.M. van den Brekel & F.J.M. Hilgers (2014). Water Uptake Performance of Hygroscopic Heat and Moisture Exchangers after 24-Hour Tracheostoma Application. Otolaryngology-Head and Neck Surgery, 150 (6), 999-1004. doi: 10.1177/0194599814527420
- C. Boer, S.H. Muller, A.D. Vincent, M.W.M. van den Brekel & F.J.M. Hilgers (2014). Ex vivo assessment and validation of water exchange performance of 23 Heat and Moisture Exchangers for laryngectomized patients. Respiratory Care, 59 (8), 1161-1171. doi: 10.4187/respcare.02840
- M.C. van Harten, M. de Ridder, O. Hamming-Vrieze, L.E. Smeele, A.J.M. Balm & M.W.M. van den Brekel (2014). The association of treatment delay and prognosis in head and neck squamous cell carcinoma (HNSCC) patients in a Dutch comprehensive cancer center. Oral Oncology, 50 (4), 282-290. doi: 10.1016/j.oraloncology.2013.12.018
- M. de Ridder, L.E. Smeele, M.W.M. van den Brekel, M.C. van Harten, M.W. Wouters & A.J.M. Balm (in press). Letter to the editor: Volume criteria for the treatment of Head and Neck cancer: Are they evidence based? Head & Neck.
- M. de Ridder, L.E. Smeele, M.W.M. van den Brekel, M.C. van Harten, M.W.J.M. Wouters & A.J.M. Balm (2014). Volume criteria for the treatment of head and neck cancer: are they evidence based? Head & Neck, 36 (5), 760-762. doi: 10.1002/hed.23555
- R. Clapham, C. Middag, F. Hilgers, J-P. Martens, M. van den Brekel & R. van Son (2014). Developing automatic articulation, voice quality and accent assessment techniques for speakers treated for advanced head and neck cancer. Speech Communication, 59, 44-54. doi: 10.1016/j.specom.2014.01.003
- A.J. Timmermans, L. Lansaat, G.V.J. Kroon, O. Hamming-Vrieze, F.J.M. Hilgers & M.W.M. van den Brekel (2014). Early oral intake after total laryngectomy does not increase pharyngocutaneous fistulization. European Archives of Oto-Rhino-Laryngology, 271 (2), 353-358. doi: 10.1007/s00405-013-2524-y
- R.P. Clapham, C.J. van As-Brooks, R.J.J.H. van Son, F.J.M. Hilgers & M.W.M. van den Brekel (in press). The relationship between acoustic signal typing and perceptual evaluation of tracheoesophageal voice quality for sustained vowels. Journal of Voice.
- A.J. Timmermans, L. Lansaat, E.A.R. Theunissen, O. Hamming-Vrieze, F.J.M. Hilgers & M.W.M. van den Brekel (2014). Predictive factors for pharyngocutaneous fistulization after total laryngectomy. The Annals of Otology Rhinology & Laryngology, 123 (3), 153-161. doi: 10.1177/0003489414522972
- C. van den Boer, S.H. Muller, A.D. Vincent, K. Züchner, M. van den Brekel & F.J.M. Hilgers (2014). Ex vivo water exchange performance and short-term clinical feasibility assessment of newly developed heat and moisture exchangers for pulmonary rehabilitation after total laryngectomy. European Archives of Oto-Rhino-Laryngology, 271 (2), 359-366. doi: 10.1007/s00405-013-2528-7
- R. de Bree, L. van der Putten, H. van Tinteren, J Wedman, W.J.G. Oyen, L. Janssen, M.W.M. van den Brekel, E.F.I. Comans, J Pruin, R.P. Takes, M.G.G. Hobbelink, R.A. Valdes-Olmos, B.F.A.M. van der Laan, M. Boers, O.S. Hoekstra & R. Leemans (in press). 18F-FDG-PET reduces the number of direct laryngoscopies in patients with suspected recurrent laryngeal carcinoma after radiotherapy: RELAPS randomised, parallel, superiority trial. Lancet.
- W.L. Lodder, W.V. Vogel, C.A. de Lange, O. Hamming-Vrieze, M.L. van Velthuysen, F.A. Pameijer, A.J. Balm & M.W. van den Brekel (2014). Detection of extranodal spread in head and neck cancer with [18F]FDG PET and MRI: improved accuracy? The Quarterly Journal of Nuclear Medicine and Molecular Imaging.
- C. van den Boer, M.C. van Harten, F.M. Hilgers, M.W.M. van den Brekel & V.P. Retèl (2014). Incidence of severe tracheobronchitis and pneumonia in laryngectomized patients: a retrospective clinical study and a European-wide survey among head and neck surgeons. European Archives of Oto-Rhino-Laryngology, 271 (12), 3297-3303. doi: 10.1007/s00405-014-2927-4
- A.J. Timmermans, M.C. van Harten, A.J. Remmelts, O. Hamming-Vrieze, W.M.C. Klop, P.J.F.M. Lohuis & M.W.M. van den Brekel (2014). Complications after transoral excision in previously irradiated head and neck cancer patients: Our experience in a retrospective cohort study of fifty-two patients. Clinical Otolaryngology and Allied Sciences, 39 (4), 245-251. doi: 10.1111/coa.12265
2013
- A.J. Timmermans, D. Brandsma, L.E. Smeele, A.W. Rosingh, M.W.M. van den Brekel & P.J.F.M. Lohuis (2013). Cervical osteomyelitis after carbon dioxide laser excision of recurrent carcinoma of the posterior pharyngeal wall. The Annals of Otology Rhinology & Laryngology, 122 (4), 273-276.
- I. Jacobi, M.A. van Rossum, L. van der Molen, F.J.M. Hilgers & M.W.M. van den Brekel (2013). Acoustic Analysis of Changes in Articulation Proficiency in Patients With Advanced Head and Neck Cancer Treated With Chemoradiotherapy. The Annals of Otology Rhinology & Laryngology, 122 (12), 754-762. doi: 10.1177/000348941312201205
- W.L. Lodder, K.G.A. Gilhuijs, C.A.H. Lange, F.A. Pameijer, A.J.M. Balm & M.W.M. van den Brekel (2013). Semi-automated primary tumor volume measurements by dynamic contrast-enhanced MRI in patients with head and neck cancer. Head & Neck, 35 (4), 521-526. doi: 10.1002/hed.22988
- W.L. Lodder, C.A.H. Lange, M.L.F. van Velthuysen, M. Hauptmann, A.J.M. Balm, M.W.M. van den Brekel & F.A. Pameijer (2013). Can extranodal spread in head and neck cancer be detected on MR imaging. Oral Oncology, 49 (6), 626-633. doi: 10.1016/j.oraloncology.2013.02.010
- J. Heukelom, O. Hamming, H. Bartelink, F. Hoebers, J. Giralt, T. Herlestam, M. Verheij, M. van den Brekel, W. Vogel, N. Slevin, E. Deutsch, J.J. Sonke, P. Lambin & C. Rasch (2013). Adaptive and innovative Radiation Treatment FOR improving Cancer treatment outcomE (ARTFORCE); a randomized controlled phase II trial for individualized treatment of head and neck cancer. BMC Cancer, 13, 84. doi: 10.1186/1471-2407-13-84
- C. van den Boer, S.H. Muller, A.D. Vincent, K. Züchner, M.W.M. van den Brekel & F.J.M. Hilgers (2013). A novel, simplified ex vivo method for measuring water exchange performance of Heat and Moisture Exchangers for postlaryngectomy pulmonary rehabilitation. Respiratory Care, 58 (9), 1449-1458. doi: 10.4187/respcare.02369
- F.J.M. Hilgers, K.J. Lorenz, H. Maier, C.A. Meeuwis, J.D.F. Kerrebijn, V. Vander Poorten, A.S. Vinck, M. Quer & M.W.M. van den Brekel (2013). Development and (pre-) clinical assessment of a novel surgical tool for primary and secondary tracheoesophageal puncture with immediate voice prosthesis insertion, the Provox Vega Puncture Set. European Archives of Oto-Rhino-Laryngology, 270 (1), 255-262. doi: 10.1007/s00405-012-1976-9[go to publisher's site]
- L. van der Molen, A.F. Kornman, M.N. Latenstein, M.W.M. van den Brekel & F.J.M. Hilgers (2013). Practice of laryngectomy rehabilitation interventions: a perspective from Europe/the Netherlands. Current Opinion in Otalaryngology & Head and Neck Surgery, 21 (3), 230-238. doi: 10.1097/MOO.0b013e3283610060[go to publisher's site]
- A.J. Remmelts, F.J.P. Hoebers, W.M.C. Klop, A.J.M. Balm, O. Hamming-Vrieze & M.W.M. van den Brekel (2013). Evaluation of lasersurgery and radiotherapy as treatment modalities in early stage laryngeal carcinoma: tumour outcome and quality of voice. European Archives of Oto-Rhino-Laryngology, 270 (7), 2079-2087. doi: 10.1007/s00405-013-2460-x
- H.S. van Monsjou, M.I. Lopez-Yurda, M. Hauptmann, M.W.M. van den Brekel, A.J.M. Balm & V.B. Wreesmann (2013). Oral and oropharyngeal squamous cell carcinoma in young patients: the Netherlands Cancer Institute experience. Head & Neck, 35 (1), 94-102. doi: 10.1002/hed.22935
- R.P. Clapham, C.J. van As-Brooks, M.W.M. van den Brekel, F.J.M. Hilgers & R.J.J.H. van Son (2013). Automatic tracheoesophageal voice typing using acoustic parameters. In F. Bimbot, C. Cerisara, C. Fougeron, G. Gravier, L. Lamel, F. Pellegrino & P. Perrier (Eds.), Interspeech 2013: 14th Annual Conference of the International Speech Communication Association: Lyon, France, August 25-29, 2013 Vol. 14. Interspeech (pp. 2162-2166). ISCA.[go to publisher's site]
- H.S. van Monsjou, V.B. Wreesmann, M.W.M. van den Brekel & A.J.M. Balm (2013). Head and neck squamous cell carcinoma in young patients. Oral Oncology, 49 (12), 1097-1102. doi: 10.1016/j.oraloncology.2013.09.001
2012
- W.L. Lodder, F.A. Pameijer, C.R.N. Rasch, M.W.M. van den Brekel & A.J.M. Balm (2012). Prognostic significance of radiologically determined neck node volume in head and neck cancer: a systematic review. Oral Oncology, 48 (4), 298-302.
- F.J.M. Hilgers, R. Dirven, Y. Wouters, I. Jacobi, H.A.M. Marres & M.W.M. van den Brekel (2012). A multicenter, prospective, clinical trial evaluating a novel adhesive baseplate (Provox StabiliBase) for peristomal attachment of postlaryngectomy pulmonary and voice rehabilitation devices. The Laryngoscope, 122 (11), 2447-2453. doi: 10.1002/lary.23469
- E.A.R. Theunissen, A.J. Timmermans, C.L. Zuur, O. Hamming-Vrieze, J.P. de Boer, F. Hilgers & M.W.M. van den Brekel (2012). Total laryngectomy for a dysfunctional larynx after (chemo)radiotherapy. Archives of Otolaryngology Head&Neck Surgery, 138 (6), 548-555. doi: 10.1001/archoto.2012.862
- M.W.M. van den Brekel, W.L. Lodder, H.V. Stel, E. Bloemena, C.R. Leemans & I. van der Waal (2012). Observer variation in the histopathologic assessment of extranodal tumor spread in lymph node metastases in the neck. Head & Neck, 34 (6), 840-845. doi: 10.1002/hed.21823
- R.P. Clapham, L. van der Molen, R.J.J.H. van Son, M. van den Brekel & F.J.M. Hilgers (2012). NKI-CCRT corpus: speech intelligibility before and after advanced head and neck cancer treated with concomitant chemoradiotherapy. In N. Calzolari, K. Choukri, T. Declerck, M. Uğur Doğan, B. Maegaard, J. Mariani, J. Odijk & S. Piperidis (Eds.), Proceedings of the Eighth International Conference on Language Resources and Evaluation (LREC'12): 23-25 May, 2012, Istanbul, Turkey (pp. 3350-3355). Paris: European Language Resources Association (ELRA).[go to publisher's site]
- H.S. van Monsjou, M.L.F. van Velthuysen, M.W.M. van den Brekel, E.S. Jordanova, C.J.M. Melief & A.J.M. Balm (2012). Human papillomavirus status in young patients with head and neck squamous cell carcinoma. International journal of cancer, 130 (8), 1806-1812.
- S.R. van Hooff, F.K.J. Leusink, P. Roepman, R.J. Baatenburg de Jong, E.J.M. Speel, M.W.M. van den Brekel, M.L.F. van Velthuysen, P.J. van Diest, R.J.J. van Es, M.A.W. Merkx, J.A. Kummer, C.R. Leemans, E. Schuuring, J.A. Langendijk, M. Lacko, M.J. de Herdt, J.C. Jansen, R.H. Brakenhoff, P.J. Slootweg, R.P. Takes & F.C.P. Holstege (2012). Validation of a gene expression signature for assessment of lymph node metastasis in oral squamous cell carcinoma. Journal of Clinical Oncology, 30 (33), 4104-4110.
- A.P. Graveland, B.J.M. Braakhuis, S.E.J. Eerenstein, R. de Bree, E. Bloemena, M. de Maaker, M.W.M. van den Brekel, F. Dijk, W.E. Mesker, H.J. Tanke, C.R. Leemans & R.H. Brakenhoff (2012). Molecular diagnosis of minimal residual disease in head and neck cancer patients. Cellular Oncology, 35 (5), 367-375. doi: 10.1007/s13402-012-0097-1
- O.R. Brouwer, W.M.C. Klop, T. Buckle, L. Vermeeren, M.W.M. van den Brekel, A.J.M. Balm, O.E. Nieweg, R.A. Valdés Olmos & F.W.B. van Leeuwen (2012). Feasibility of sentinel node biopsy in head and neck melanoma using a hybrid radioactive and fluorescent tracer. Annals of Surgical Oncology, 19 (6), 1988-1994.
- N.S. van den Berg, O.R. Brouwer, W.M.C. Klop, B. Karakullukcu, C.L. Zuur, I.B. Tan, A.J.M. Balm, M.W.M. van den Brekel, R.A. Valdés Olmos & F.W.B. van Leeuwen (2012). Concomitant radio- and fluorescence-guided sentinel lymph node biopsy in squamous cell carcinoma of the oral cavity using ICG-(99m)Tc-nanocolloid. European Journal of Nuclear Medicine and Molecular Imaging, 39 (7), 1128-1136.
- S. Samant, M.W.M. van den Brekel, M.S. Kies, J. Wan, K.T. Robbins, D.I. Rosenthal, C. Rasch & R.S. Weber (2012). Concurrent chemoradiation for adenoid cystic carcinoma of the head and neck. Head & Neck, 34 (9), 1263-1268.
- O. Hamming-Vrieze, S.R. van Kranen, S. van Beek, W. Heemsbergen, M. van Herk, M.W.M. van den Brekel, J.J. Sonke & C.R.N. Rasch (2012). Evaluation of tumor shape variability in head-and-neck cancer patients over the course of radiation therapy using implanted gold markers. International Journal of Radiation Oncology Biology Physics, 84 (2), e201-e207.
2011
- M.W.M. van den Brekel, A.J.M. Balm, P.J.F.M. Lohuis & J.P.W. van der Veen (2011). 10th International Symposium on Head And Neck Skin Cancer. Expert Review of Anticancer Therapy, 11 (7), 1013-1015.
- L. Vermeeren, R.A. Valdés Olmos, W.M.C. Klop, I.M.C. van der Ploeg, O.E. Nieweg, A.J.M. Balm & M.W.M. van den Brekel (2011). SPECT/CT for sentinel lymph node mapping in head and neck melanoma. Head & Neck, 33 (1), 1-6.
- W.L. Lodder, H.J. Teertstra, I.B. Tan, F.A. Pameijer, L.E. Smeele, M.L.F. van Velthuysen & M.W.M. van den Brekel (2011). Tumour thickness in oral cancer using an intra-oral ultrasound probe. European Radiology, 21 (1), 98-106. doi: 10.1007/s00330-010-1891-7
2010
- F.J.M. Hilgers, A.J.M. Balm, M.W.M. van den Brekel & I.B. Tan (2010). Voice restoration. In M. Remacle & H.E. Eckel (Eds.), Surgery of larynx and trachea (pp. 245-256). Berlin [etc.]: Springer.
- M.B. Karakullukcu, P.J. Lohuis, M.W.M. van den Brekel & F.J.M. Hilgers (2010). Sealing of small postlaryngectomy pharyngocutaneous fistulas with voice prosthesis. The Laryngoscope, 120 (10), 1971-1973. doi: 10.1002/lary.21071
- F.J.M. Hilgers, A.H. Ackerstaff, I. Jacobi, A.J.M. Balm, I.B. Tan & M.W.M. van den Brekel (2010). Prospective clinical phase II study of two new indwelling voice prostheses (Provox Vega 22.5 and 20 Fr) and a novel anterograde insertion device (Provox Smart Inserter). The Laryngoscope, 120 (6), 1135-1143. doi: 10.1002/lary.20925
- F.J.M. Hilgers, A.H. Ackerstaff, M. van Rossum, I. Jacobi, A.J.M. Balm, I.B. Tan & M.W.M. van den Brekel (2010). Clinical phase I/feasibility study of the next generation indwelling Provox voice prosthesis (Provox Vega). Acta Oto-Laryngologica, 130 (4), 511-519.
- F.J.M. Hilgers & M.W.M. van den Brekel (2010). Vocal and speech rehabilitation following laryngectomy. In P.W. Flint, B.H. Haughey, V.J. Lund, J.K. Niparko, M.A. Richardson, K.T. Robbins & J.R. Thomas (Eds.), Cummings otolaryngology: head & neck surgery. - 5th ed (pp. 1594-1610). Philadelphia, PA: Mosby Elsevier.
- M.C. de Jong, J. Pramana, J.L. Knegjens, A.J.M. Balm, M.W.M. van den Brekel, M. Hauptmann, A.C. Begg & C.R.N. Rasch (2010). HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors. Radiotherapy and oncology, 95 (3), 365-370.
- H.S. van Monsjou, A.J.M. Balm, M.M. van den Brekel & V.B. Wreesmann (2010). Oropharyngeal squamous cell carcinoma: a unique disease on the rise? Oral Oncology, 46 (11), 780-785. doi: 10.1016/j.oraloncology.2010.08.011
- M.C. Jong, J. Pramana, J.E. van der Wal, M. Lacko, C.J. Peutz-Kootstra, J.M. Jong, R.P. Takes, J.H. Kaanders, B.F. van der Laan, J. Wachters, J.C. Jansen, C.R. Rasch, M.L.F. van Velthuysen, R. Grénman, F.J. Hoebers, E. Schuuring, M.W.M. van den Brekel & A.C. Begg (2010). CD44 expression predicts local recurrence after radiotherapy in larynx cancer. Clinical Cancer Research, 16 (21), 5329-5338.
- L. Vermeeren, R.A. Valdés Olmos, W.M.C. Klop, A.J.M. Balm & M.W.M. van den Brekel (2010). A portable gamma-camera for intraoperative detection of sentinel nodes in the head and neck region. The Journal of Nuclear Medicine, 51 (5), 700-703.
- W.L. Lodder, M. Hauptmann, H.J. Teertstra, M.W.M. van den Brekel & A.J.M. Balm (2010). Letter to the editor: "Is preoperative ultrasonography accurate in measuring tumor thickness and predicting the incidence of cervical metastasis in oral cancer?". Oral Oncology, 46 (8), 627;-author reply 628.
- M.H. Valstar, M.W.M. van den Brekel & L.E. Smeele (2010). Interpretation of treatment outcome in the clinically node-negative neck in primary parotid carcinoma: A systematic review of the literature. Head & Neck, 32 (10), 1402-1411.
2009
- G.B. van den Broek, M. Wildeman, C.R.N. Rasch, N. Armstrong, E. Schuuring, A.C. Begg, L.H.J. Looijenga, R. Scheper, J.E. van der Wal, L. Menkema, P.J. van Diest, A.J.M. Balm, M.L.F. van Velthuysen & M.W.M. van den Brekel (2009). Molecular markers predict outcome in squamous cell carcinoma of the head and neck after concomitant cisplatin-based chemoradiation. International journal of cancer, 124 (11), 2643-2650.
- L. van der Putten, G.B. van den Broek, R. de Bree, M.W.M. van den Brekel, A.J.M. Balm, F.J.P. Hoebers, P. Doornaert, C.R. Leemans & C.R.N. Rasch (2009). Effectiveness of salvage selective and modified radical neck dissection for regional pathologic lymphadenopathy after chemoradiation. Head & Neck, 31 (5), 593-603. doi: 10.1002/hed.20987
- I.M.C. van der Ploeg, R.A. Valdés Olmos, B.B.R. Kroon, M.W.J.M. Wouters, M.W.M. van den Brekel, W.V. Vogel, C.A. Hoefnagel & O.E. Nieweg (2009). The yield of SPECT/CT for anatomical lymphatic mapping in patients with melanoma. Annals of Surgical Oncology, 16 (6), 1537-1542.
- T.W. Geurts, M.L.F. van Velthuysen, F. Broekman, T. Hooft van Huysduynen, M.W.M. van den Brekel, N. van Zandwijk, H. van Tinteren, P. Nederlof, A.J.M. Balm & R.H. Brakenhoff (2009). Differential Diagnosis of Pulmonary Carcinoma Following Head and Neck Cancer by Genetic Analysis. Clinical Cancer Research, 15 (3), 980-985.
- A. Kreeft, I.B. Tan, M.W.M. van den Brekel, F.J. Hilgers & A.J.M. Balm (2009). The surgical dilemma of 'functional inoperability' in oral and oropharyngeal cancer: current consensus on operability with regard to functional results. Clinical Otolaryngology, 34 (2), 140-146. doi: 10.1111/j.1749-4486.2009.01884.x
- P.J.F.M. Lohuis, M.L. Tan, K. Bonte, M.W.M. van den Brekel, A.J.M. Balm & H.B. Vermeersch (2009). Superficial parotidectomy via facelift incision. The Annals of Otology Rhinology & Laryngology, 118 (4), 276-280.
2008
- M.C. Borgemeester, M.W.M. van den Brekel, H. van Tinteren, L.E. Smeele, F.A. Pameijer, M.L.F. van Velthuysen & A.J.M. Balm (2008). Ultrasound-guided aspiration cytology for the assessment of the clinically N0 neck: factors influencing its accuracy. Head & Neck, 30 (11), 1505-1513. doi: 10.1002/hed.20903
- M. van den Brekel & F.J.M. Hilgers (2008). Preoperative workup of the neck in Head and Neck Squamous Cell Carcinoma. In C.R. Cernea, F.L. Dias, D. Fliss, R.A. Lima, E.N. Myers & W.I. Wei (Eds.), Pearls and pitfalls in head and neck surgery: practical tips to minimize complications (pp. 34-35). Basel [etc.]: Karger.
- F.J.M. Hilgers & M. van den Brekel (2008). Practical tips for voice rehabilitation after pharyngolaryngectomy. In C.R. Cernea, F.L. Dias, D. Fliss, R.A. Lima, E.N. Myers & W.I. Wei (Eds.), Pearls and pitfalls in head and neck surgery: practical tips to minimize complications (pp. 96-97). Basel [etc.]: Karger.
- P.J. Tanis, O.E. Nieweg, M.W.M. van den Brekel & A.J.M. Balm (2008). Dilemma of clinically node-negative head and neck melanoma: Outcome of "watch and wait" policy, elective lymph node dissection, and sentinel node biopsy - A systematic review. Head & Neck, 30 (3), 380-389.
- F.J.M. Hilgers, J. Soolsma, A.H. Ackerstaff, F.J.M. Balm, I.B. Tan & M.W.M. van den Brekel (2008). A thin tracheal silicone washer to solve periprosthetic leakage in laryngectomies: direct results and long-term clinical effects. The Laryngoscope, 118 (4), 640-645.[go to publisher's site]
- I.M. Oskam, F. Hoebers, A.J.M. Balm, F. van Coevorden, E.M. Bais, A.M. Hart & M.W.M. van den Brekel (2008). Neck management in medullary thyroid carcinoma. European Journal of Surgical Oncology, 34 (1), 71-76.
- F.J.P. Hoebers, M. Kartachova, J. de Bois, M.W.M. van den Brekel, H. van Tinteren, M. van Herk, C.R.N. Rasch, R.A. Valdés Olmos & M. Verheij (2008). 99mTc Hynic-rh-Annexin V scintigraphy for in vivo imaging of apoptosis in patients with head and neck cancer treated with chemoradiotherapy. European Journal of Nuclear Medicine and Molecular Imaging, 35 (3), 509-518.
- J. Soolsma, M.W. van den Brekel, A.H. Ackerstaff, A.J. Balm, B. Tan & F.J. Hilgers (2008). Long-term results of Provox ActiValve, solving the problem of frequent Candida - and 'underpressure'-related voice prosthesis replacements. The Laryngoscope, 118 (2), 252-257.[go to publisher's site]
2007
- D.J. Menger, M.W.M. van den Brekel & F.J.M. Hilgers (2007). Een bijzonder beloop van een glottisch larynxcarcinoom. Nederlands tijdschrift voor keel- neus- en oorheelkunde, 2007 (13), 151-154.
- J. Pramana, M.W.M. van den Brekel, M.L.F. van Velthuysen, L.F.A. Wessels, D.S. Nuyten, I. Hofland, D. Atsma, N. Pimentel, F.J.P. Hoebers, C.R.N. Rasch & A.C. Begg (2007). Gene expression profiling to predict outcome after chemoradiation in head and neck cancer. International Journal of Radiation Oncology Biology Physics, 69 (5), 1544-1552.
- A.T. van Goor, R. Kröger, H.M. Klomp, M.A.A. de Jong, M.W.M. van den Brekel & A.J.M. Balm (2007). Introduction of lymphangiography and percutaneous embolization of the thoracic duct in a stepwise approach to the management of chylous fistulas. Head & Neck, 29 (11), 1017-1023.
- S.M. Reinartz, L.J. Schot, R.G. Riedl, F. Oldenburger & M.W.M. van den Brekel (2007). Presentation of two cases of nasal type NK/T-cell lymphoma. European Archives of Oto-Rhino-Laryngology, 264 (1), 39-43.
- G.B. van den Broek, V.B. Wreesmann, M.W.M. van den Brekel, C.R.N. Rasch, A.J.M. Balm & P.H. Rao (2007). Genetic abnormalities associated with chemoradiation resistance of head and neck squamous cell carcinoma. Clinical Cancer Research, 13 (15 Part 1), 4386-4391.
2006
- G.B. van den Broek, A.J.M. Balm, M.W.M. van den Brekel, M. Hauptmann, J.H. Schornagel & C.R.N. Rasch (2006). Relationship between clinical factors and the incidence of toxicity after intra-arterial chemoradiation for head and neck cancer. Radiotherapy and oncology, 81 (2), 143-150.
- G.B. van den Broek, C.R.N. Rasch, F.A. Pameijer, E. Peter, M.W.M. van den Brekel & A.J.M. Balm (2006). Response measurement after intraarterial chemoradiation in advanced head and neck carcinoma: magnetic resonance imaging and evaluation under general anesthesia? Cancer, 106 (8), 1722-1729.
- F.J.M. Hilgers, A.J.M. Balm, M.W.M. van den Brekel & I.B. Tan (2006). Problembehandlung bei der prothetischen Stimmrehabilitation nach (totaler) Laryngektomie. Journal der Deutschen Gesellschaft für Plastische und Wiederherstellungschirurgie, 33, 41-51.
2014
- S.A.C. Kraaijenga, L. van der Molen, M.W.M. van den Brekel & F.J.M. Hilgers (2014). Current assessment and treatment strategies of dysphagia in head and neck cancer patients: a systematic review of the 2012/13 literature. Current Opinion in Supportive and Palliative Care, 8 (2), 152-163. doi: 10.1097/SPC.0000000000000050
2013
- W.L. Lodder, C.A.H. Lange, H.J. Teertstra, F.A. Pameijer, M.W.M. van den Brekel & A.J.M. Balm (2013). Value of MR and CT Imaging for Assessment of Internal Carotid Artery Encasement in Head and Neck Squamous Cell Carcinoma. International Journal of Surgical Oncology, 2013, 968758.
2012
- M.W.M. van den Brekel & F.J.M. Hilgers (2012). Preoperative workup of the neck in head and neck squamous cell carcinoma. In C.R. Cernea (Ed.), Pearls and pitfalls in head and neck surgery; practical tips to minimize complications; second revised and extended edition (pp. 36-37). s.l: Karger.
2011
- R. Clapham, F. Hilgers, M. van den Brekel & R. van Son (2011). An exploration into automatic phonological feature evaluation of tracheoesophageal speech. In W. Zonneveld, H. Quené & W. Heeren (Eds.), Sound and sounds: studies presented to M.E.H. (Bert) Schouten on the occasion of his 65th birthday (pp. 69-79). Utrecht: Utrecht Institute of Linguistics OTS.
- A.J.M. Balm, M.W.M. van den Brekel, I.B. Tan & F.J.M. Hilgers (2011). The indwelling voice prosthesis for speech rehabilitation after total laryngectomy: a safe approach. Otolaryngologia polska = Polish journal of otolaryngology, 65 (6), 402-409.
2010
- R. Cevizci, B. Karakullukçu, M.W.M. van den Brekel & A.J. Balm (2010). Laser excision of a typical carcinoid tumor of the larynx: a case report. KULAK BURUN BOGAZ IHTIS DERG, 20 (6), 305-308.
- A.J.M. Balm, M.L.F. van Velthuysen, F.J.P. Hoebers, W.V. Vogel & M.W.M. van den Brekel (2010). Diagnosis and treatment of a neck node swelling suspicious for a malignancy: an algorithmic approach. International Journal of Surgical Oncology, 2010, 581540.
2009
- L. Vermeeren, W.M.C. Klop, M.W.M. van den Brekel, A.J.M. Balm, O.E. Nieweg & R.A. Valdés Olmos (2009). Sentinel Node Detection in Head and Neck Malignancies: Innovations in Radioguided Surgery. Journal of Oncology, 2009, 681746.
2008
- P.C. Wever, J.C. Bos, M.W.M. van den Brekel, D. de Jong, L.P.M.J. BovǸe, M.J. Kersten, J.F.P. Schellekens & J.M. Kerst (2008). Een waarschijnlijk geval van difterie. Tijdschrift voor Infectieziekten, 3 (6), 230-235.
2015
- F.J.M. Hilgers & M.W.M. van den Brekel (2015). Vocal and Speech Rehabilitation Following Laryngectomy. In P.W. Flint, B.H. Haughey, V. Lund, J.K. Niparko, K.T. Robbins, J. Regan Thomas & M.M. Lesperance (Eds.), Cummings Otolaryngology - Head & neck surgery. - 6th ed. - Vol. 2 (pp. 1732-1750). Philadelphia, PA: Elsevier.
2013
- F.M. Hilgers, S.H. Muller, R.J. Scheenstra & M. van den Brekel (2013). Aktuelle Forschung zur Verbesserung der Wärme und Feuchtigkeitskapazität von HME. In K. Lorenz (Ed.), Pulmonale Rehabilitation nach Laryngektomie (UNI-MED science) (pp. 43-52). Bremen: UNI-MED-Verlag.
- F.J.M. Hilgers, I.B. Tan & M.W.M. van den Brekel (2013). Comprehensive (prosthetic) voice, pulmonary and olfaction rehabilitation after total laryngectomy. In Head and Neck Surgery. - 2nd ed. New Delhi, India: Chris de Souza,Jaypee Brothers Medical Publishers (P) LTD.
2012
- A.J. Timmermans, M.W.M. van den Brekel, L. van der Molen, A. Navran, T.F. Nijssen & F.J.M. Hilgers (2012). Nieuwe ontwikkelingen in behandeling en revalidatie bij hoofd-halskanker. Nederlands Tijdschrift voor Geneeskunde, 156 (41), 1719-1724.
- F.J.M. Hilgers & M. van den Brekel (2012). Practical tips for voice rehabilitation after pharyngolaryngectomy. In R.C. Claudio (Ed.), Pearls and pitfalls in head and neck surgery: practical tips to minimize complications. - 2nd ed (pp. 94-95). Basel: Karger.
- A. Ackerstaff, F.M. Hilgers & M. van den Brekel (2012). Bedeutung von HME für die ganzheitliche Rehabilitation nach LE. In K.J. Lorenz (Ed.), Pulmonale Rehabilitation nach Laryngektomie (UNI-MED science) (pp. 35-41). Bremen: UNI-MED-Verlag.
- A.J. Timmermans, M. Krap, F.J.M. Hilgers & M.W.M. van den Brekel (2012). Spraakrevalidatie na een totale laryngectomie. Nederlands Tijdschrift voor Tandheelkunde, 119 (7-8), 357-361. doi: 10.5177/ntvt.2012.07/08.12132
- M. van den Brekel (2012). Hoofd-hals oncologie onder spanning. (2012, November 15). Amsterdam: University of Amsterdam, Amsterdam Center for Language and Communication.[go to publisher's site]
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NKL-AVL Amsterdam
Hoofd-hals chirurg -
AMC Amsterdam
KNO arts
