General information

I am assistant professor in the group 'Molecular Biology and Microbial Food Safety' headed by Prof Stanley Brul at the Swammerdam Institute for Life Sciences (SILS) at the University of Amsterdam (UvA). For a general description of the research interests of the group refer to:

• The group: SILS/MB&MFS

• Staff: Prof. dr Stanley Brul

• Staff: dr Gertien Smits

Personal research interest

My personal research interest is on mitochondrial genetics and function (yeast, man, nematodes), including topics like regulation of translation, respiratory complex assembly and regulation of transcription (mainly in bakers yeast). Recently the focus has shifted to anti-retroviral drug-induced mitochondrial dysfunction that has become apparent in HIV-1 infected patients (see below). To address fundamental questions concerning mitochondrial (dys)function the nematode Caenorhabditis elegans has been introduced in the lab and employed as a  model organism.  For an overview of recent results follow the link to see the poster presented at the SILS researchday in January 2008.
Additional research activities are supervision of fundamental and applied research projects concerning food spoilage microorganisms such as Bacillus subtilis .

• Poster recentresults

Student Projects

Within our 'mitochondrial (dys)function' group (staff, PhD student and a technician) there are possibilities for Bachelor-, Master- and HBO students to perform a research project. For a general description of the research project follow the link. For more information contact Hans van der Spek.

• Student Project

Publications

Follow the link to see the publications.

• Publications via DARE (not complete)

• Geen nevenwerkzaamheden