If the enzymes HDAC1 and HDAC2 do not function properly, changes can occur in the gene expression, which in turn could possibly contribute to the development of cancer. For his PhD dissertation, Roel Wilting focuses on class I HDAC1 and HDAC2 enzymes and particularly their role in cell cycle regulation, hematopoiesis and the discovery of their tumour-suppressive nature.
R.H. Wilting, Inactive the Two-Faced HDAC-Brake: Cell Cycle Regulation and Tumor Suppression by Histone Deacetylases HDAC1 and HDAC2.
Prof. M.M.S. van Lohuizen
Dr J.H. Dannenberg (Genmab)
This event will be open to the public.