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The generation of mice with a deficiency of the AE2 protein has made it possible to characterise the phenotypes of AE2 deficiency. By isolating fibroblasts in these mice, Pablo Hiche created a cellular model in which he studied if, and to what extent, AE2 effectively regulates intracellular pH in a cell type that is not polarised, epithelial or secretory.

Event details of The role of the AE2 protein in intracellular pH
Date 9 October 2013
Time 14:00 -15:00
Location Agnietenkapel

P. Mardones Hiche, On the Role of the Anion Exchanger 2 (AE2, SLC4A2) in Intracellular pH Homeostatis and Bone Remodeling.


Prof. R.P.J. Oude Elferink


Oudezijds Voorburgwal 229 - 231
1012 EZ Amsterdam


Free of charge