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Phosphoinositides are implicated in virtually all aspects of cellular warfare. They help to maintain the structure of biomembranes, but are also essential signal transduction molecules. This is illustrated by Ptdlns(4,5)P2, a versatile and important phosphoinositide that regulates many cellular processes, including cell survival, calcium homeostasis, vesicular trafficking, cytokinesis, stress responses and cell adhesion. Willem-Jan Keune examines the biochemical and functional aspects of Ptdlns5P and the PIP4Ks that determine its level in the cell.

Event details of Phospoinositides in oxidative stress signalling and cancer
Date 21 November 2013
Time 12:00 -13:00
Location Agnietenkapel

W.J.H. Keune, Phospoinositides and Lipid Kinases in Oxidative Stress Signalling and Cancer.


Prof. G.J. Borst


Dr N. Divecha (NKI-AVL)


Oudezijds Voorburgwal 229 - 231
1012 EZ Amsterdam


This event will be open to the public.