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Endothelial cells (ECs) provide a barrier between blood and the underlying tissue. Upon stimulation, specific storage organelles, designated WeibelPalade Bodies (WPBs), fuse with the plasmamembrane and release various components into the bloodstream. The main component of WPBs is Von Willebrand Factor (VWF), a multimeric glycoprotein which upon its release by endothelial cells is converted into ultra large VWF strings which capture blood platelets. For her PhD dissertation, Bieuwke Dragt aims to unravel the biogenesis and functional significance of VWF strings.

Event details of Formation and biological function of Von Willebrand Factor
Date 20 December 2013
Time 13:00 -14:00
Location Aula - Lutherse kerk

B.S. Dragt, Unraveling von Willebrand factor Extracellular Traps.


Prof. J.J. Voorberg (Sanquin)


Dr B. de Laat (UMC Utrecht)

Aula - Lutherse kerk

Singel 411
1012 XM Amsterdam


This event will be open to the public.