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In many cases, the methods commonly used to obtain detailed structural data on protein complexes, such as X-ray diffraction, do not work on larger complexes. Other methods such as cryo-electron microscopy are also ineffective. Hansuk Buncherd applies the chemical cross-linking of proteins in combination with mass spectrometry analysis of proteolytic peptides in order to obtain structural data on protein complexes.

Event details of Obtaining structural data on protein complexes
Date 2 December 2013
Time 14:00 -15:00
Location Agnietenkapel

H. Buncherd, Development of Enrichment Methods for Cross-Linked Peptides to Study the Dynamic Topology of Large Protein Complexes by Mass Spectrometry.

Supervisor

Prof. C.G. de Koster

Co-supervisor

Dr L. de Jong

Agnietenkapel

Oudezijds Voorburgwal 229 - 231
1012 EZ Amsterdam

Entrance

This event will be open to the public.