Glia play an important role in the physiology of the brain and are closely associated with the pathogenesis and progression of Alzheimer’s Disease (AD). A lot is still unknown about the molecular and functional changes in glia. By using an unbiased genome-wide approach, Marie Orre sets out to characterise the molecular phenotype of reactive astrocytes and activated microglia in relation to AD.
A.M. Orre, Glia in Alzheimer's Disease and Aging: Molecular Mechanisms Underlying Astrocyte and Microglia Reactivity.
Prof. E.M. Hol
Dr W. Kamphuis (KNAW)
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