Froukje Nolte’s aim is to improve patient selection for the percutaneous coronary intervention (PCI) by proposing new clinical indices for the assessment of functional stenosis severity using combined measurements of intracoronary pressure and flow velocity that do not require maximal vasodilation of the coronary vascular bed, and by testing the hypothesis of collateral flow augmentation secondary to epicardial narrowing in relation to the presence of reversible ischemia and the potential contribution to increased minimal microvascular resistance to total myocardial ischemia.
F. Nolte, Improved Assessment of Functional Severity of Coronary Artery Stenosis by Analysis of Combined Intracoronary Pressure and Flow Velocity Signals.
Prof. J.A.E. Spaan
Prof. J.J. Piek
Dr M. Siebes
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