Anxiety disorders rank among the most prevalent and chronic forms of psychopathology. While commonly used therapeutic techniques, such as exposure therapy, are effective in reducing fear, there are high rates of relapse. According to the traditional view on memory, once an emotional memory has been stored in the brain through the process of consolidation, the memory remains as a permanent trace. However, exciting insights from neuroscience showed that through re-exposure, a consolidated fear memory can return to a plastic state. From this plastic state the memory has to reconsolidate in order to endure, depending on new protein synthesis. Dieuwke Sevenster aims to unravel the mechanisms that determine whether memory reactivation effectively induces reconsolidation.
D. Sevenster, Fear Memory Uncovered: Prediction Error as the Key to Memory Plasticity.
Prof. M. Kindt
Prof. T.R.J. Beckers
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