The main goal of a total knee arthroplasty (TKA) is to relieve pain and restore function in a severly diseased or injured knee joint. Although many improvements have been made in surgical techniques and implant design, knee arthroplasties are not able to fully restore a knee to its pre osteoarthritis or pre injury state. One major problem that remains is the proportion of patients continuing to experience varying degrees of pain after TKA. The location of this persisting pain is usually in the anterior part of the knee. Stefan Breugem analyses anterior knee pain (AKP) after TKA and discusses some of its clinical implications. His PhD thesis is intended as a contribution to the process of better understanding AKP after TKA from a number of perspectives.