In the last decade, the mesodiencephalic dopaminergic (mdDA) system has extensively been studied for its association with Parkinson’s Disease (PD). Although some progress has been made, the molecular mechanisms behind specific neuronal vulnerability of the Substantia Nigra (SN) subset of mdDA neurons in PD have remained largely unclear. Jesse Veenvliet uses various strategies to elucidate the molecular diversity of mdDA neurons in more detail, and relates this molecular diversity to the selective degeneration of SN neurons in PD.
J. Veenvliet, The Born Identity: Molecular Mechanisms of Dopaminergic Subset Specification.
Prof. M.P. Smidt
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