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Pancreatic cancer is a very difficult to treat tumour type with a very poor prognosis. Within this cancer, so-called Hedgehog (Hh) ligands are produced by tumour cells and signal to the surrounding tumour microenvironment, which has been shown to have tumour promoting functions. One of the main cellular components of the tumour microenvironment, also called tumour stroma, are fibroblasts that get activated by signals from the tumour cells such as Hh. Helene Damhofer aims to gain new insight into different layers of the regulation of Hh signaling and the stromal response in pancreatic cancer.

Event details of Hedgehog ligand signaling in pancreatic cancer
Date 30 April 2015
Time 14:00 -15:00
Location Agnietenkapel

H. Damhofer, Opening New Doors: Hedgehog Signaling and the Pancreatic Cancer Stroma.

Supervisor

Prof. J.P. Medema

Co-supervisor

Dr M.F. Bijlsma

Agnietenkapel

Oudezijds Voorburgwal 229 - 231
1012 EZ Amsterdam

Entrance

This event is open the public.