Aging is a universal biological process characterised by the gradual decline of a multitude of physiological functions that leads to an increasing probability of death. To date we have a poor understanding of what actually causes aging. Recent results of research on worms and mice have led researchers to question the free radical theory as the primary or exclusive cause of aging. Another theory proposes that aging is driven by genetic programming that is useful for organisms in early life but becomes detrimental at later stages. Marco Lezzerini investigates whether one of the most important developmental pathways, the Wnt signalling pathway, plays a functional role in the aging of the roundworm Caenorhabditis elegans.
M. Lezzerini: Aging in Caenorhabditis elegans ; the Role of Wnt Signalling.
Prof. S. Brul
Dr Y. Budovskaya
This event is open to the public.