Bregje van Oorschot’s research focuses on the two contrasting sides of radiotherapy: tumour control and normal tissue toxicity. The aim of radiation therapy is to kill cancerous cells with the highest possible radiation dose, by inducing as much DNA damage as possible. On the other hand, escalation of the radiation dose will also increase of normal tissue damage and hence of the normal tissue complication rate. Van Oorschot explores the molecular processes that occur after radiation treatment, not only in cancer cells but also in normal cells, in the hope that this will improve our insight into the radiation responses and possibly lead to the identification of new therapeutic targets or biomarkers.
B. van Oorschot: Tumor Control and Normal Tissue Toxicity: the Two Faces of Radiotherapy.
Prof. J.P. Medema
Prof. L.J.A. Stalpers
Dr N.A.P. Franken
Dr H. Vrieling (LUMC)
This event is open to the public.