G proteins, or guanine nucleotide-binding proteins, are signalling proteins that function as molecular switches. G proteins are found in the cells of organisms ranging from ancient unicellar organisms to plants, fungi and animals and play an important role in the way cells communicate with their environment. Jakobus van Unen investigates G protein signalling in living cells, looking at the way G proteins interact with other classes of proteins. He uses advanced fluorescence microscopy techniques to follow protein interactions in living cells.
J. van Unen: Spatiotemporal aspects of G protein signaling: where GPCRs and Rho GTPases meet.
Prof. T.W.J. Gadella
Dr J. Goedhart
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