Liver surgery is often the only curative treatment for patients with a tumour of the liver. During resection, the blood supply to the liver is surgically stopped to prevent excessive blood loss. The accompanying shortage of oxygen causes a sterile inflammatory response once the blood flow is restored. This harmful response is know as ischemia/reperfusion injury. Rowan van Golen studies a number of pathophysiological aspects of this type of injury, and the interaction between parenchymal liver pathology and surgery-induced liver injury.