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Nuclear receptors are transcription factors that regulate the expression of genes involved in all aspects of cellular biology. Duco Koenis studies the nuclear receptors Nur77 and liver X receptor (LXR). As central regulators of inflammation and metabolism, these factors play important roles in the pathogenesis of diseases driven by excessive inflammation and dysregulated metabolism, such as atherosclerosis. Koenis provides greater insight into how the activity of Nur77 and LXR is regulated and how they in turn regulate metabolism, inflammatory response and differentiation of various cells.

Event details of Role of nuclear receptors in hematological and inflammation-driven disorders
Date 6 July 2018
Time 14:00 -15:00
Location Agnietenkapel
Room Location

D.S. Koenis: Nuclear Receptors and Their Co-Factors in Hematological and Inflammation-Driven Disorders.


Prof. C.J.M. de Vries

Prof. N. Zelcer


Dr C.J.M. de Vries

Dr S. Huveneers


Room Location

Oudezijds Voorburgwal 229 - 231
1012 EZ Amsterdam


This event is open to the public.