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Wei, Z., Knaus, T., Liu, Y., Zhai, Z., Gargano, A. F. G., Rothenberg, G., Yan, N., & Mutti, F. G. (2023). A high-performance electrochemical biosensor using an engineered urate oxidase. Chemical Communications, 59(52), 8071-8074 . https://doi.org/10.1039/d3cc01869e
2022
Bhardwaj, S. K., Knaus, T., Garcia, A., Yan, N., & Mutti, F. G. (2022). Bacterial Peroxidase on Electrochemically Reduced Graphene Oxide for Highly Sensitive H2O2 Detection. ChemBioChem, 23(17), [e202200346]. https://doi.org/10.1002/cbic.202200346[details]
Corrado, M. L., Knaus, T., Schwaneberg, U., & Mutti, F. G. (2022). High-Yield Synthesis of Enantiopure 1,2-Amino Alcohols from L-Phenylalanine via Linear and Divergent Enzymatic Cascades. Organic Process Research and Development, 26(7), 2085-2095. https://doi.org/10.1021/acs.oprd.1c00490[details]
Croci, F., Vilím, J., Adamopoulou, T., Tseliou, V., Schoenmakers, P. J., Knaus, T., & Mutti, F. G. (2022). Continuous Flow Biocatalytic Reductive Amination by Co-Entrapping Dehydrogenases with Agarose Gel in a 3D-Printed Mould Reactor. ChemBioChem, 23(22), [e202200549]. https://doi.org/10.1002/cbic.202200549[details]
Knaus, T., Corrado, M. L., & Mutti, F. G. (2022). One-Pot Biocatalytic Synthesis of Primary, Secondary, and Tertiary Amines with Two Stereocenters from α,β-Unsaturated Ketones Using Alkyl-Ammonium Formate. ACS Catalysis, 12(23), 14459-14475. https://doi.org/10.1021/acscatal.2c03052[details]
Corrado, M. L., Knaus, T., & Mutti, F. G. (2021). High Regio- and Stereoselective Multi-enzymatic Synthesis of All Phenylpropanolamine Stereoisomers from β-Methylstyrene. ChemBioChem, 22(13), 2345-2350. https://doi.org/10.1002/cbic.202100123[details]
Corrado, M. L., Tseliou, V., Houwman, J. A., Böhmer, W., Vilím, J., Masman, M. F., Knaus, T., & Mutti, F. G. (2021). Hydrogen-borrowing conversion of alcohols into optically active primary amines by combination of alcohol dehydrogenases and amine dehydrogenases. In J. Whittall, & P. W. Sutton (Eds.), Applied Biocatalysis: The Chemist's Enzyme Toolkit (pp. 455-468). Wiley. https://doi.org/10.1002/9781119487043.ch11[details]
Tseliou, V., Böhmer, W., Corrado, M. L., Masman, M. F., Knaus, T., & Mutti, F. G. (2021). Asymmetric reductive amination of ketones catalysed by amine dehydrogenases. In J. Whittall, & P. W. Sutton (Eds.), Applied Biocatalysis: The Chemist's Enzyme Toolkit (pp. 221-231). Wiley. https://doi.org/10.1002/9781119487043.ch5[details]
Tseliou, V., Schilder, D., Masman, M. F., Knaus, T., & Mutti, F. G. (2021). Generation of Oxidoreductases with Dual Alcohol Dehydrogenase and Amine Dehydrogenase Activity. Chemistry-A European Journal, 27(10), 3315-3325. https://doi.org/10.1002/chem.202003140[details]
Vilím, J., Knaus, T., & Mutti, F. (2021). Aerobic synthesis of aromatic nitriles from alcohols and ammonia using galactose oxidase. In J. Whittall, & P. W. Sutton (Eds.), Applied Biocatalysis: The Chemist's Enzyme Toolkit (pp. 449-455). Wiley. https://doi.org/10.1002/9781119487043.ch11[details]
2020
Tseliou, V., Knaus, T., Vilím, J., Masman, M. F., & Mutti, F. G. (2020). Kinetic Resolution of Racemic Primary Amines Using Geobacillus stearothermophilus Amine Dehydrogenase Variant. ChemCatChem, 12(8), 2184-2188. https://doi.org/10.1002/cctc.201902085[details]
Vilím, J., Knaus, T., & Mutti, F. G. (2020). Biocatalyzed Aerobic Oxidation Reaction. In E. Mejía (Ed.), Catalytic Aerobic Oxidations (pp. 131-180). (Catalysis Series; No. 39). Royal Society of Chemistry. https://doi.org/10.1039/9781839160332-00131[details]
2019
Bohmer, W., Knaus, T., Volkov, A., Slot, T. K., Shiju, N. R., Cassimjee, K. E., & Mutti, F. G. (2019). Highly efficient production of chiral amines in batch and continuous flow by immobilized ω-transaminases on controlled porosity glass metal-ion affinity carrier. Journal of Biotechnology, 291, 52-60. https://doi.org/10.1016/j.jbiotec.2018.12.001[details]
Corrado, M. L., Knaus, T., & Mutti, F. G. (2019). Regio- and stereoselective multi-enzymatic aminohydroxylation of β-methylstyrene using dioxygen, ammonia and formate. Green Chemistry, 21(23), 6246-6251. https://doi.org/10.1039/c9gc03161h[details]
Gacs, J., Zhang, W., Knaus, T., Mutti, F. G., Arends, I. W. C. E., & Hollmann, F. (2019). A Photo-Enzymatic Cascade to Transform Racemic Alcohols into Enantiomerically Pure Amines. Catalysts, 9(4), [305]. https://doi.org/10.3390/catal9040305[details]
Houwman, J. A., Knaus, T., Costa, M., & Mutti, F. G. (2019). Efficient synthesis of enantiopure amines from alcohols using resting E. coli cells and ammonia. Green Chemistry, 21(14), 3846-3857. https://doi.org/10.1039/c9gc01059a
Tseliou, V., Knaus, T., Masman, M. F., Corrado, M. L., & Mutti, F. G. (2019). Generation of amine dehydrogenases with increased catalytic performance and substrate scope from ε-deaminating L-Lysine dehydrogenase. Nature Communications, 10, [3717]. https://doi.org/10.1038/s41467-019-11509-x[details]
Tseliou, V., Masman, M. F., Böhmer, W., Knaus, T., & Mutti, F. G. (2019). Mechanistic Insight into the Catalytic Promiscuity of Amine Dehydrogenases: Asymmetric Synthesis of Secondary and Primary Amines. ChemBioChem, 20(6), 800-812. https://doi.org/10.1002/cbic.201800626[details]
Bohmer, W., Knaus, T., & Mutti, F. G. (2018). Hydrogen-Borrowing Alcohol Bioamination with Coimmobilized Dehydrogenases. ChemCatChem, 10(4), 731-735. https://doi.org/10.1002/cctc.201701366[details]
Corrado, M. L., Knaus, T., & Mutti, F. G. (2018). A Chimeric Styrene Monooxygenase with Increased Efficiency in Asymmetric Biocatalytic Epoxidation. ChemBioChem, 19(7), 679-686. https://doi.org/10.1002/cbic.201700653[details]
Knaus, T., Tseliou, V., Humphreys, L. D., Scrutton, N. S., & Mutti, F. G. (2018). A biocatalytic method for the chemoselective aerobic oxidation of aldehydes to carboxylic acids. Green Chemistry, 20(17), 3931-3943. https://doi.org/10.1039/c8gc01381k[details]
Knaus, T., Böhmer, W., & Mutti, F. G. (2017). Amine dehydrogenases: efficient biocatalysts for the reductive amination of carbonyl compounds. Green Chemistry, 19(2), 453-463. https://doi.org/10.1039/c6gc01987k[details]
Knaus, T., Cariati, L., Masman, M. F., & Mutti, F. G. (2017). In vitro biocatalytic pathway design: orthogonal network for the quantitative and stereospecific amination of alcohols. Organic & Biomolecular Chemistry, 15(39), 8313-8325. https://doi.org/10.1039/c7ob01927k
2016
Knaus, T., Paul, C. E., Levy, C. W., de Vries, S., Mutti, F. G., Hollmann, F., & Scrutton, N. S. (2016). Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes. Journal of the American Chemical Society, 138(3), 1033-1039. https://doi.org/10.1021/jacs.5b12252[details]
Mutti, F., Knaus, T., Levy, C. W., Scrutton, N. S., Paul, C. E. & Hollmann, F. (2016). 5CPN : Crystal structure of XenA from Pseudomonas putida in complex with an NADH mimic (mAc). RCSB-PDB. https://doi.org/10.2210/pdb5cpn/pdb
Scrutton, N. S., Levy, C. W., Mutti, F., Hollmann, F., Knaus, T. & Paul, C. E. (2016). 5CPM : XenA from Pseudomonas putida in complex with NADPH4.. RCSB-PDB. https://doi.org/10.2210/pdb5cpm/pdb
Levy, C. W., Paul, C. E., Knaus, T., Hollmann, F., Mutti, F. & Scrutton, N. S. (2016). 5CPL : The crystal structure of Xenobiotic reductase A (XenA) from Pseudomonas putida in complex with a nicotinamide mimic (mNH2). RCSB-PDB. https://doi.org/10.2210/pdb5cpl/pdb
2015
Knaus, T., Mutti, F. G., Humphreys, L. D., Turner, N. J., & Scrutton, N. S. (2015). Systematic methodology for the development of biocatalytic hydrogen-borrowing cascades: application to the synthesis of chiral α-substituted carboxylic acids from α-substituted α,β-unsaturated aldehydes. Organic & Biomolecular Chemistry, 13(1), 223-233. https://doi.org/10.1039/c4ob02282c
Mutti, F. G., Knaus, T., Scrutton, N. S., Breuer, M., & Turner, N. J. (2015). Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades. Science, 349(6255), 1525-1529. https://doi.org/10.1126/science.aac9283[details]
Mutti, F., Tseliou, V., Knaus, T., & Masman, M. F. (2020). L-Lysine epsilon-dehydrogenase variants and uses thereof. (Patent No. WO 2020165417 A1 20200130).
Mutti, F., Vilím, J., & Knaus, T. (2020). Process for the manufacture of nitrile compounds. (Patent No. WO 2020020844 A1 20200130).
2015
Baldenius, K., Breuer, M., Ditrich, K., Navickas, V., Mutti, F., Knaus, T., & Turner, N. (2015). Redox self-sufficient bioamination of alcohols.
Membership / relevant position
Mutti, F., Knaus, T., Böhmer, W., Corrado, M. L., Tseliou, V. & Vilím, J. (2018-). member, HRSMC.
Talk / presentation
Knaus, T. (speaker) (2019). an amine dehydrogenase variant with increased catalytic performance and expanded substrate scope, XXII SINAQO—South American Organic Chemistry Conference, Mendoza.
2016
Levy, C. W., Paul, C. E., Knaus, T., Hollmann, F., Mutti, F. & Scrutton, N. S. (2016). 5CPL : The crystal structure of Xenobiotic reductase A (XenA) from Pseudomonas putida in complex with a nicotinamide mimic (mNH2). RCSB-PDB. https://doi.org/10.2210/pdb5cpl/pdb
Scrutton, N. S., Levy, C. W., Mutti, F., Hollmann, F., Knaus, T. & Paul, C. E. (2016). 5CPM : XenA from Pseudomonas putida in complex with NADPH4.. RCSB-PDB. https://doi.org/10.2210/pdb5cpm/pdb
Mutti, F., Knaus, T., Levy, C. W., Scrutton, N. S., Paul, C. E. & Hollmann, F. (2016). 5CPN : Crystal structure of XenA from Pseudomonas putida in complex with an NADH mimic (mAc). RCSB-PDB. https://doi.org/10.2210/pdb5cpn/pdb
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