Prof. dr. S.M. (Marieke) van Ham
Faculteit der Natuurwetenschappen, Wiskunde en Informatica
Swammerdam Institute for Life Sciences
Bezoekadres
- Science Park 904
Postadres
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Postbus 1212
1000 BE Amsterdam
Contactgegevens
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Publicaties
2023
- T2B Consortium (2023). Distinct dynamics of antigen-specific induction and differentiation of different CD11c+Tbet+ B-cell subsets. Journal of Allergy and Clinical Immunology, 152(3), 689-699.e6. https://doi.org/10.1016/j.jaci.2023.02.020
- T2B Consortium, Koers, J., Sciarrillo, R., Derksen, N. I. L., Vletter, E. M., Fillié-Grijpma, Y. E., Raveling-Eelsing, E., Graça, N. A. G., Leijser, T., Pas, H. H., Laura van Nijen-Vos, L., Braham, M. V. J., Buisman, A. M., de Jong, J., Schriek, A. I., Tio-Gillen, A. P., Teng, Y. K. O., Steenhuis, M., Swaneveld, F. H., ... Rispens, T. (2023). Differences in IgG autoantibody Fab glycosylation across autoimmune diseases. Journal of Allergy and Clinical Immunology, 151(6), 1646-1654. https://doi.org/10.1016/j.jaci.2022.10.035
- Verstegen, N. J. M., Pollastro, S., Unger, P. P. A., Marsman, C., Elias, G., Jorritsma, T., Streutker, M., Bassler, K., Haendler, K., Rispens, T., Schultze, J. L., Brinke, A. T., Beyer, M., & van Ham, S. M. (2023). Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates. eLife, 12, Article e83578. https://doi.org/10.7554/elife.83578
- van Dam, K. P. J., Takkenberg, R. B., Bemelman, F. J., de Wit, J., Busch, M. H., van Ham, S. M., Verstegen, N. J. M., Tas, S. W., & T2B! immunity against SARS-CoV-2 study group (2023). Disease activity in patients with immune-mediated inflammatory diseases after SARS-CoV-2 vaccinations. Journal of autoimmunity, 135, Article 102984. https://doi.org/10.1016/j.jaut.2022.102984
van Dam, K. P. J., Tas, S. W., Takkenberg, R. B., Bemelman, F. J., de Wit, J., Busch, M. H., Verstegen, N. J. M., van Ham, S. M., & T2B! immunity against SARS-CoV-2 study group (2023). Primary SARS-CoV-2 infection in patients with immune-mediated inflammatory diseases: long-term humoral immune responses and effects on disease activity. BMC Infectious Diseases, 23(1), Article 332. https://doi.org/10.1186/s12879-023-08298-6- van Kempen, Z. L. E., Hogenboom, L., Toorop, A. A., Steenhuis, M., Stalman, E. W., Kummer, L. Y. L., van Dam, K. P. J., Bloem, K., ten Brinke, A., van Ham, S. M., Kuijpers, T. W., Wolbink, G. J., Loeff, F. C., Wieske, L., Eftimov, F., Rispens, T., Strijbis, E. M. M., Killestein, J., & T2B! immunity against SARS-CoV-2 study group (2023). Ocrelizumab Concentration Is a Good Predictor of SARS-CoV-2 Vaccination Response in Patients with Multiple Sclerosis. Annals of Neurology, 93(1), 103-108. https://doi.org/10.1002/ana.26534 [details]
- van Kempen, Z. L. E., Stalman, E. W., Steenhuis, M., Kummer, L. Y. L., van Dam, K. P. J., Wilbrink, M. F., Ten Brinke, A., van Ham, S. M., Kuijpers, T., Rispens, T., Eftimov, F., Wieske, L., Killestein, J., & T2B! immunity against SARS-CoV-2 study group (2023). SARS-CoV-2 omicron breakthrough infections in patients with multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 94(4), 280-283. https://doi.org/10.1136/jnnp-2022-330100 [details]
- van Osch, T. L. J., Steuten, J., Nouta, J., Koeleman, C. A. M., Bentlage, A. E. H., Heidt, S., Mulder, A., Voorberg, J., van Ham, S. M., Wuhrer, M., ten Brinke, A., & Vidarsson, G. (2023). Phagocytosis of platelets opsonized with differently glycosylated anti-HLA hIgG1 by monocyte-derived macrophages. Platelets (London), 34(1), Article 2129604. Advance online publication. https://doi.org/10.1080/09537104.2022.2129604 [details]
2022
- Boekel, L., Besten, Y. R., Hooijberg, F., Wartena, R., Steenhuis, M., Vogelzang, E., Leeuw, M., Atiqi, S., Tas, S. W., Lems, W. F., van Ham, S. M., Eftimov, F., Stalman, E. W., Wieske, L., Kuijpers, T. W., Voskuyl, A. E., van Vollenhoven, R. F., Gerritsen, M., Krieckaert, C., ... Wolbink, G. (2022). SARS-CoV-2 breakthrough infections in patients with immune-mediated inflammatory diseases during the omicron dominant period. The Lancet. Rheumatology, 4(11), e747-e750. https://doi.org/10.1016/S2665-9913(22)00221-1 [details]
- Boekel, L., Hooijberg, F., Vogelzang, E. H., Besten, Y. R., Leeuw, M., Atiqi, S., van Vollenhoven, R. F., Wijbrandts, C. A., Gerritsen, M., Krieckaert, C., Dijkshoorn, B., Bakhlakh, S., Crooijmans, J. J., Voskuyl, A., van der Horst-Bruinsma, I. E., Lems, W., Kuijpers, T. W., van Ham, S. M., Wieske, L., ... Wolbink, G. (2022). Antibody development and disease severity of COVID-19 in non-immunised patients with rheumatic immune-mediated inflammatory diseases: data from a prospective cohort study. RMD OPEN, 8(1), Article e002035. https://doi.org/10.1136/rmdopen-2021-002035
- Boekel, L., Tas, S. W., Takkenberg, R. B., Bemelman, F. J., de Wit, J., Verstegen, N. J. M., van Ham, S. M., & T2B! immunity against SARS-CoV-2 study group (2022). Breakthrough SARS-CoV-2 infections with the delta (B.1.617.2) variant in vaccinated patients with immune-mediated inflammatory diseases using immunosuppressants: a substudy of two prospective cohort studies. The Lancet. Rheumatology, 4(6), e417-e429. https://doi.org/10.1016/S2665-9913(22)00102-3 [details]
- Bos, A. V., van Gool, M. M. J., Breedveld, A. C., van der Mast, R., Marsman, C., Bouma, G., van de Wiel, M. A., van Ham, S. M., Mebius, R. E., & van Egmond, M. (2022). Fcα Receptor-1-Activated Monocytes Promote B Lymphocyte Migration and IgA Isotype Switching. International Journal of Molecular Sciences, 23(19), Article 11132. https://doi.org/10.3390/ijms231911132 [details]
- Koers, J., Marsman, C., Steuten, J., Tol, S., Derksen, N. I. L., ten Brinke, A., van Ham, S., & Rispens, T. (2022). Oxygen level is a critical regulator of human B cell differentiation and IgG class switch recombination. Frontiers in Immunology, 13, Article 1082154. https://doi.org/10.3389/fimmu.2022.1082154 [details]
- Koers, J., Pollastro, S., Tol, S., Pico-Knijnenburg, I., Derksen, N. I. L., van Schouwenburg, P. A., van der Burg, M., van Ham, S. M., & Rispens, T. (2022). CD45RB Glycosylation and Ig Isotype Define Maturation of Functionally Distinct B Cell Subsets in Human Peripheral Blood. Frontiers in Immunology, 13, Article 891316. https://doi.org/10.3389/fimmu.2022.891316 [details]
- Marsman, C., Verhoeven, D., Koers, J., Rispens, T., ten Brinke, A., van Ham, S. M., Kuijpers, T. W., & T2B Consortium (2022). Optimized Protocols for In-Vitro T-Cell-Dependent and T-Cell-Independent Activation for B-Cell Differentiation Studies Using Limited Cells. Frontiers in Immunology, 13, Article 815449. https://doi.org/10.3389/fimmu.2022.815449 [details]
- Marsman, C., Verstegen, N. J. M., Streutker, M., Jorritsma, T., Boon, L., Ten Brinke, A., & van Ham, S. M. (2022). Termination of CD40L co-stimulation promotes human B cell differentiation into antibody-secreting cells. European journal of immunology, 52(10), 1662-1675. https://doi.org/10.1002/eji.202249972 [details]
- Palomares Cabeza, V., Kummer, L. Y. L., Wieske, L., Hagen, R. R., Duurland, M., Konijn, V. A. L., van Dam, K. P. J., Stalman, E. W., van de Sandt, C. E., Boekel, L., Verstegen, N. J. M., Steenhuis, M., Rispens, T., Tas, S. W., Wolbink, G., Killestein, J., Kuijpers, T. W., van Ham, S. M., Eftimov, F., ... Target-to-B! (T2B!) SARS-CoV-2 study group (2022). Longitudinal T-Cell Responses After a Third SARS-CoV-2 Vaccination in Patients With Multiple Sclerosis on Ocrelizumab or Fingolimod. Neurology® Neuroimmunology & Neuroinflammation, 9(4), Article e1178. https://doi.org/10.1212/NXI.0000000000001178 [details]
- Stalman, E. W., Tas, S. W., Takkenberg, R. B., Bemelman, F. J., de Wit, J., Verstegen, N. J. M., van Ham, S. M., & T2B! immunity against SARS-CoV-2 study group (2022). Breakthrough infections with the SARS-CoV-2 omicron (B.1.1.529) variant in patients with immune-mediated inflammatory diseases. Annals of the Rheumatic Diseases, 81(12), 1757-1766. https://doi.org/10.1136/ard-2022-222904 [details]
- Verstegen, N. J. M., Hagen, R. R., van den Dijssel, J., Kuijper, L. H., Kreher, C., Ashhurst, T., Kummer, L. Y. L., Steenhuis, M., Duurland, M., de Jongh, R., de Jong, N., van der Schoot, C. E., Bos, A. V., Mul, E., Kedzierska, K., van Dam, K. P. J., Stalman, E. W., Boekel, L., Wolbink, G., ... T2B! immunity against SARS-CoV-2 study group (2022). Immune dynamics in SARS-CoV-2 experienced immunosuppressed rheumatoid arthritis or multiple sclerosis patients vaccinated with mRNA-1273. eLife, 11, Article e77969. https://doi.org/10.7554/eLife.77969 [details]
- Wieske, L., Takkenberg, R. B., Tas, S. W., Bemelman, F. J., ten Brinke, A., Verstegen, N. J. M., van Ham, S. M., & T2B! immunity against SARS-CoV-2 study group (2022). Risk factors associated with short-term adverse events after SARS-CoV-2 vaccination in patients with immune-mediated inflammatory diseases. BMC Medicine, 20, Article 100. https://doi.org/10.1186/s12916-022-02310-7 [details]
- Wieske, L., Tas, S. W., Takkenberg, R. B., Verstegen, N. J. M., Zwinderman, K. A. H., van Ham, S. M., & T2B! immunity against SARS-CoV-2 study group (2022). Humoral responses after second and third SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders on immunosuppressants: a cohort study. The Lancet. Rheumatology, 4(5), e338-e350. https://doi.org/10.1016/S2665-9913(22)00034-0 [details]
- van Dam, K. P. J., Hogenboom, L., Stalman, E. W., Kummer, L. Y. L., Steenhuis, M., Keijser, J. B. D., ten Brinke, A., van Ham, S. M., Kuijpers, T. W., Rispens, T., Wieske, L., Eftimov, F., Strijbis, E. M., Killestein, J., van Kempen, Z. L. E., & T2B! immunity against SARS-CoV-2 study group (2022). Longitudinal SARS-CoV-2 humoral response in MS patients with and without SARS-CoV-2 infection prior to vaccination. Frontiers in Neurology, 13, Article 1032830. https://doi.org/10.3389/fneur.2022.1032830 [details]
- van Kempen, Z. L. E., Wieske, L., Stalman, E. W., Kummer, L. Y. L., van Dam, P. J., Volkers, A. G., Boekel, L., Toorop, A. A., Strijbis, E. M. M., Tas, S. W., Wolbink, G. J., Löwenberg, M., van Sandt, C., ten Brinke, A., Verstegen, N. J. M., Steenhuis, M., Kuijpers, T. W., van Ham, S. M., Rispens, T., ... T2B! immunity against SARS-CoV-2 study group (2022). Longitudinal humoral response after SARS-CoV-2 vaccination in ocrelizumab treated MS patients: To wait and repopulate? Multiple sclerosis and related disorders, 57, Article 103416. https://doi.org/10.1016/j.msard.2021.103416 [details]
- van den Dijssel, J., Hagen, R. R., de Jongh, R., Steenhuis, M., Rispens, T., Geerdes, D. M., Mok, J. Y., Kragten, A. H. M., Duurland, M. C., Verstegen, N. J. M., van Ham, S. M., van Esch, W. J. E., van Gisbergen, K. P. J. M., Hombrink, P., ten Brinke, A., & van de Sandt, C. E. (2022). Parallel detection of SARS-CoV-2 epitopes reveals dynamic immunodominance profiles of CD8+ T memory cells in convalescent COVID-19 donors. Clinical & translational immunology, 11(10), Article e1423. https://doi.org/10.1002/cti2.1423 [details]
2021
- Boekel, L., Hooijberg, F., van Kempen, Z. L. E., Vogelzang, E. H., Tas, S. W., Killestein, J., Nurmohamed, M. T., Boers, M., Kuijpers, T. W., van Ham, S. M., Eftimov, F., Wieske, L., Rispens, T., & Wolbink, G. J. (2021). Perspective of patients with autoimmune diseases on COVID-19 vaccination. The Lancet. Rheumatology, 3(4), e241-e243. https://doi.org/10.1016/S2665-9913(21)00037-0 [details]
- Boekel, L., Kummer, L. Y., van Dam, K. P. J., Hooijberg, F., van Kempen, Z., Vogelzang, E. H., Wieske, L., Eftimov, F., van Vollenhoven, R., Kuijpers, T. W., van Ham, S. M., Tas, S. W., Killestein, J., Boers, M., Nurmohamed, M. T., Rispens, T., & Wolbink, G. (2021). Adverse events after first COVID-19 vaccination in patients with autoimmune diseases. The Lancet. Rheumatology, 3(8), e542-e545. https://doi.org/10.1016/S2665-9913(21)00181-8
- Boekel, L., Steenhuis, M., Hooijberg, F., Besten, Y. R., van Kempen, Z. L. E., Kummer, L. Y., van Dam, K. P. J., Stalman, E. W., Vogelzang, E. H., Cristianawati, O., Keijzer, S., Vidarsson, G., Voskuyl, A. E., Wieske, L., Eftimov, F., van Vollenhoven, R., Kuijpers, T. W., van Ham, S. M., Tas, S. W., ... Wolbink, G. (2021). Antibody development after COVID-19 vaccination in patients with autoimmune diseases in the Netherlands: a substudy of data from two prospective cohort studies. The Lancet. Rheumatology, 3(11), e778-e788. https://doi.org/10.1016/S2665-9913(21)00222-8 [details]
- Merino Tejero, E., Lashgari, D., García-Valiente, R., Gao, X., Crauste, F., Robert, P. A., Meyer-Hermann, M., Rodríguez Martínez, M., van Ham, S. M., Guikema, J. E. J., Hoefsloot, H., & van Kampen, A. H. C. (2021). Multiscale Modeling of Germinal Center Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells Differentiation as Regulated by Antigen Affinity-Based Tfh Cell Help. Frontiers in Immunology, 11, Article 620716. https://doi.org/10.3389/fimmu.2020.620716 [details]
- Saris, A., Steuten, J., Schrijver, D. P., van Schijndel, G., Zwaginga, J. J., van Ham, S. M., & ten Brinke, A. (2021). Inhibition of Dendritic Cell Activation and Modulation of T Cell Polarization by the Platelet Secretome. Frontiers in Immunology, 12, Article 631285. https://doi.org/10.3389/fimmu.2021.631285 [details]
- Steenhuis, M., van Mierlo, G., Derksen, N. I., Ooijevaar-de Heer, P., Kruithof, S., Loeff, F. L., Berkhout, L. C., Linty, F., Reusken, C., Reimerink, J., Hogema, B., Zaaijer, H., van de Watering, L., Swaneveld, F., van Gils, M. J., Bosch, B. J., van Ham, S. M., Ten Brinke, A., Vidarsson, G., ... Rispens, T. (2021). Dynamics of antibodies to SARS-CoV-2 in convalescent plasma donors. Clinical & translational immunology, 10(5), Article e1285. https://doi.org/10.1002/cti2.1285
- Unger, P-P. A., Verstegen, N. J. M., Marsman, C., Jorritsma, T., Rispens, T., ten Brinke, A., & van Ham, S. M. (2021). Minimalistic In Vitro Culture to Drive Human Naive B Cell Differentiation into Antibody-Secreting Cells. Cells, 10(5), Article 1183. https://doi.org/10.3390/cells10051183 [details]
- Verstegen, N. J. M., Ubels, V., Westerhoff, H. V., van Ham, S. M., & Barberis, M. (2021). System-Level Scenarios for the Elucidation of T Cell-Mediated Germinal Center B Cell Differentiation. Frontiers in Immunology, 12, Article 734282. https://doi.org/10.3389/fimmu.2021.734282 [details]
- Zeerleder, S., Engel, R., Zhang, T., Roem, D., van Mierlo, G., Wagenaar-Bos, I., van Ham, S. M., Wuhrer, M., Wouters, D., & Jongerius, I. (2021). Sugar Matters: Improving In Vivo Clearance Rate of Highly Glycosylated Recombinant Plasma Proteins for Therapeutic Use. Pharmaceuticals (Basel, Switzerland), 14(1). https://doi.org/10.3390/ph14010054
- van Asten, S. D., Unger, P-P., Marsman, C., Bliss, S., Jorritsma, T., Thielens, N. M., van Ham, S. M., & Spaapen, R. M. (2021). Soluble FAS Ligand Enhances Suboptimal CD40L/IL-21-Mediated Human Memory B Cell Differentiation into Antibody-Secreting Cells. The journal of immunology, 207(2), 449-458. https://doi.org/10.4049/jimmunol.2001390 [details]
2020
- Marsman, C., Jorritsma, T., ten Brinke, A., & van Ham, S. M. (2020). Flow Cytometric Methods for the Detection of Intracellular Signaling Proteins and Transcription Factors Reveal Heterogeneity in Differentiating Human B Cell Subsets. Cells, 9(12), Article 2633. https://doi.org/10.3390/cells9122633 [details]
- Rijvers, L., Melief, M-J., van Langelaar, J., van der Vuurst de Vries, R. M., Wierenga-Wolf, A. F., Koetzier, S. C., Priatel, J. J., Jorritsma, T., van Ham, S. M., Hintzen, R. Q., & van Luijn, M. M. (2020). The Role of Autoimmunity-Related Gene CLEC16A in the B Cell Receptor-Mediated HLA Class II Pathway. The journal of immunology, 205(4), 945-956. https://doi.org/10.4049/jimmunol.1901409
- Unger, P-PA., Lighaam, L. C., Vermeulen, E., Kruithof, S., Makuch, M., Culver, E. L., van Bruggen, R., Remmerswaal, E. B. M., ten Berge, I. J. M., Emmens, R. W., Niessen, H. W. M., Barnes, E., Wolbink, G. J., van Ham, S. M., & Rispens, T. (2020). Divergent chemokine receptor expression and the consequence for human IgG4 B cell responses. European journal of immunology, 50(8), 1113-1125. https://doi.org/10.1002/eji.201948454 [details]
2019
- Cargill, T., Makuch, M., Sadler, R., Lighaam, L. C., Peters, R., van Ham, M., Klenerman, P., Bateman, A., Rispens, T., Barnes, E., & Culver, E. L. (2019). Activated T-Follicular Helper 2 Cells Are Associated With Disease Activity in IgG4-Related Sclerosing Cholangitis and Pancreatitis. Clinical and translational gastroenterolgy, 10(4), Article e00020. https://doi.org/10.14309/ctg.0000000000000020
- Koster, B. D., Santegoets, S. J. A. M., Harting, J., Baars, A., van Ham, S. M., Scheper, R. J., Hooijberg, E., de Gruijl, T. D., & van den Eertwegh, A. J. M. (2019). Autologous tumor cell vaccination combined with systemic CpG-B and IFN-α promotes immune activation and induces clinical responses in patients with metastatic renal cell carcinoma: a phase II trial. Cancer immunology and immunotherapy, 68(6), 1025-1035. https://doi.org/10.1007/s00262-019-02320-0 [details]
- Saris, A., Kerkhoffs, J. L., Norris, P. J., van Ham, S. M., ten Brinke, A., Brand, A., van der Meer, P. F., & Zwaginga, J. J. (2019). The role of pathogen-reduced platelet transfusions on HLA alloimmunization in hemato-oncological patients. Transfusion, 59(2), 470-481. https://doi.org/10.1111/trf.15056 [details]
- Verstegen, N. J. M., Unger, P-PA., Walker, J. Z., Nicolet, B. P., Jorritsma, T., van Rijssel, J., Spaapen, R. M., de Wit, J., van Buul, J. D., ten Brinke, A., & van Ham, S. M. (2019). Human B Cells Engage the NCK/PI3K/RAC1 Axis to Internalize Large Particles via the IgM-BCR. Frontiers in Immunology, 10, Article 415. https://doi.org/10.3389/fimmu.2019.00415 [details]
- Zaal, A., van Ham, S. M., & ten Brinke, A. (2019). Differential effects of anaphylatoxin C5a on antigen presenting cells, roles for C5aR1 and C5aR2. Immunology letters, 209, 45-52. https://doi.org/10.1016/j.imlet.2019.03.014 [details]
- ten Brinke, A., Martinez-Llordella, M., Cools, N., Hilkens, C. M. U., van Ham, S. M., Sawitzki, B., Geissler, E. K., Lombardi, G., Trzonkowski, P., & Martinez-Caceres, E. (2019). Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective. Frontiers in Immunology, 10, Article 181. https://doi.org/10.3389/fimmu.2019.00181 [details]
- van Langelaar, J., Rijvers, L., Janssen, M., Wierenga-Wolf, A. F., Melief, M-J., Siepman, T. A., de Vries, H. E., Unger, P-PA., van Ham, S. M., Hintzen, R. Q., & van Luijn, M. M. (2019). Induction of brain-infiltrating T-bet-expressing B cells in multiple sclerosis. Annals of Neurology, 86(2), 264-278. https://doi.org/10.1002/ana.25508 [details]
2018
- Lighaam, L. C., Unger, P-PA., Vredevoogd, D. W., Verhoeven, D., Vermeulen, E., Turksma, A. W., ten Brinke, A., Rispens, T., & van Ham, S. M. (2018). In vitro-Induced Human IL-10+ B Cells Do Not Show a Subset-Defining Marker Signature and Plastically Co-express IL-10 With Pro-Inflammatory Cytokines. Frontiers in Immunology, 9, Article 1913. https://doi.org/10.3389/fimmu.2018.01913 [details]
- Saris, A., Peyron, I., van der Meer, P. F., Stuge, T. B., Zwaginga, J. J., van Ham, S. M., & ten Brinke, A. (2018). Storage-Induced Platelet Apoptosis Is a Potential Risk Factor for Alloimmunization Upon Platelet Transfusion. Frontiers in Immunology, 9, Article 1251. https://doi.org/10.3389/fimmu.2018.01251 [details]
- Saris, A., Tomson, B., Brand, A., Mulder, A., Claas, F. H., Lorinser, J., Scharenberg, J., van Ham, S. M., Ten Brinke, A., Zwaginga, J. J., & van der Meer, P. F. (2018). Platelets from donors with consistently low HLA-B8, -B12, or -B35 expression do not undergo antibody-mediated internalization. Blood, 131(1), 144-152. https://doi.org/10.1182/blood-2017-07-799270
- Souwer, Y., Groot Kormelink, T., Taanman-Kueter, E. W., Muller, F. J., van Capel, T. M. M., Varga, D. V., Bar-Ephraim, Y. E., Teunissen, M. B. M., van Ham, S. M., Kuijpers, T. W., Wouters, D., Meyaard, L., & de Jong, E. C. (2018). Human TH17 cell development requires processing of dendritic cell-derived CXCL8 by neutrophil elastase. Journal of Allergy and Clinical Immunology, 141(6), 2286-2289.e5. https://doi.org/10.1016/j.jaci.2018.01.003
- Unger, P. P., Makuch, M., Aalbers, M., Derksen, N. I. L., ten Brinke, A., Aalberse, R. C., Rispens, T., & van Ham, S. M. (2018). Repeated vaccination with tetanus toxoid of plasma donors with pre-existing specific IgE transiently elevates tetanus-specific IgE but does not induce allergic symptoms. Clinical and Experimental Allergy, 48(4), 479-482. https://doi.org/10.1111/cea.13107 [details]
- van de Bovenkamp, F. S., Derksen, N. I. L., Ooijevaar-de Heer, P., van Schie, K. A., Kruithof, S., Berkowska, M. A., van der Schoot, C. E., IJspeert, H., van der Burg, M., Gils, A., Hafkenscheid, L., Toes, R. E. M., Rombouts, Y., Plomp, R., Wuhrer, M., van Ham, S. M., Vidarsson, G., & Rispens, T. (2018). Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region. Proceedings of the National Academy of Sciences of the United States of America, 115(8), 1901-1906. https://doi.org/10.1073/pnas.1711720115
2017
- Emmens, R. W., Oedayrajsingh-Varma, M., Woudstra, L., Kamp, O., Meinster, E., van Dijk, A., Helder, M. N., Wouters, D., Zeerleder, S., van Ham, S. M., de Jong, N., Niessen, H. W. M., Juffermans, L. J. M., & Krijnen, P. A. J. (2017). A comparison in therapeutic efficacy of several time points of intravenous StemBell administration in a rat model of acute myocardial infarction. Cytotherapy, 19(1), 131-140. https://doi.org/10.1016/j.jcyt.2016.10.004
- Emmens, R. W., Wouters, D., Zeerleder, S., van Ham, S. M., Niessen, H. W. M., & Krijnen, P. A. J. (2017). On the value of therapeutic interventions targeting the complement system in acute myocardial infarction. Translational Research, 182, 103-122. https://doi.org/10.1016/j.trsl.2016.10.005
- Fuchs, A., Gliwiński, M., Grageda, N., Spiering, R., Abbas, A. K., Appel, S., Bacchetta, R., Battaglia, M., Berglund, D., Blazar, B., Bluestone, J. A., Bornhäuser, M., Ten Brinke, A., Brusko, T. M., Cools, N., Cuturi, M. C., Geissler, E., Giannoukakis, N., Gołab, K., ... Trzonkowski, P. (2017). Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Frontiers in Immunology, 8, 1844. https://doi.org/10.3389/fimmu.2017.01844
- Ten Brinke, A., Marek-Trzonkowska, N., Mansilla, M. J., Turksma, A. W., Piekarska, K., Iwaszkiewicz-Grześ, D., Passerini, L., Locafaro, G., Puñet-Ortiz, J., van Ham, S. M., Hernandez-Fuentes, M. P., Martínez-Cáceres, E. M., & Gregori, S. (2017). Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses. Frontiers in Immunology, 8, Article 1870. https://doi.org/10.3389/fimmu.2017.01870
- Zaal, A., Dieker, M., Oudenampsen, M., Turksma, A. W., Lissenberg-Thunnissen, S. N., Wouters, D., van Ham, S. M., & Ten Brinke, A. (2017). Anaphylatoxin C5a Regulates 6-Sulfo-LacNAc Dendritic Cell Function in Human through Crosstalk with Toll-Like Receptor-Induced CREB Signaling. Frontiers in Immunology, 8, Article 818. https://doi.org/10.3389/fimmu.2017.00818
- Zaal, A., Nota, B., Moore, K. S., Dieker, M., van Ham, S. M., & ten Brinke, A. (2017). TLR4 and C5aR crosstalk in dendritic cells induces a core regulatory network of RSK2, PI3Kβ, SGK1, and FOXO transcription factors. Journal of leukocyte biology, 102(4), 1035-1054. https://doi.org/10.1189/jlb.2MA0217-058R [details]
Lidmaatschap / relevante positie
- van Ham, M. (2022-2027). Consortiumpartner and co-applicant of ImmuneHealthSeed funded by Collaborative Health Foundations and Health Holland, ImmuneHealthSeed.
- van Ham, M. (2022-2024). Member of External Scientific Advisory Board, Germans Trias i Pujol Research Institute (IGTP), Badalona, Barcelona, Spain, SAB IGTP Spain.
- van Ham, M. (2022-2027). Secretary General of Board of European Federation of Immunological Societies (EFIS: https://www.efis.org/), European Federation of Immunological Societies .
- van Ham, M. (2020-2024). Co-project leader and work package leader Humoral and Cellular Immunity of 2 ZonMW COVID-19 Programs “Immunity against SARS-CoV-2 in (…), Target to B Immunity against SARS-CoV-2.
- van Ham, M. (2020-2037). (Co-)founder of strategic public-private-partnership (sPPP) ImmuneHealthXL (HealthHolland; http://www.immunehealthxl.nl/).The mission of (…), sPPP ImmuneHealthXL. http://www.immunehealthxl.nl/
- van Ham, M. (2019-2023). Supervisory Board member, overall Trainer and working group leader of INsTRuCT (Innovative Training in Myeloid Regulatory Cell Therapy), ITN Grant (…), INsTRuCT consortium Horizon 2020. https://instruct-h2020.eu/
- van Ham, M. (2018-2022). Vice-program leader, Project Management Board member and working group leader of national public private partnership Target to B!, grant by (…), Public Private Partnership Target to B. https://www.target-to-b.nl/
- van Ham, M. (2018-2022). Supervisory Board member and working group leader of national PPP (Public Private Partnership) DC4Balance grant by Collaborative Health Foundations (…), Public Private Partnership (PPP) DC4Balance. https://www.immunehealthxl.nl/current-projects/dc4balance
- van Ham, M. (2018-2025). Member of EU H2020 consortium RESTORE (tolDC therapy in MS and immunomonitoring thereof).ReSToRe aims to develop cell therapies for multiple (…), ReSToRe consortium Horizon 2020.
- van Ham, M. (2017-2022). Board Member of Dutch Society for Immunology, NVVI/DSI.
Mediaoptreden
- van Ham, M. (11-09-2021). Coronavaccins werken ook bij patiënt met auto-immuunziekte [Print] Volkskrant and Trouw (and taken over by ANP/NOS/Linda/Radio 1/Radar/NLTimes). Coronavaccins werken ook bij patiënt met auto-immuunziekte.
- van Ham, M. (15-01-2019). Dokters van Morgen [Television]. NPO 1 Dokters van Morgen.
Andere
- van Ham, M. (participant) (2-9-2018 - 5-9-2018). 5th European Congress of Immunology, Amsterdam. President of 5th European Congress of Immunology, European Federation of Immunological Societies (organising a conference, workshop, ...).
2024
- Lighaam, L. C. (2024). The features and dynamics of IgG4 B cell responses: Insights in B cell-mediated immune tolerance. [Thesis, fully internal, Universiteit van Amsterdam]. [details]
- Oskam, S. M. (2024). Immunoglobulin M: Structure, function and specificity in health and autoimmunity. [Thesis, fully internal, Universiteit van Amsterdam]. [details]
- Verkerk, T. (2024). Exploring the interplay between immune cells and tumors: Insights into antigen presentation and tumor immune evasion. [Thesis, fully internal, Universiteit van Amsterdam]. [details]
2023
- Koers, J. (2023). B cell and antibody differentiation: The contribution of glycans to repertoire diversification and classification. [Thesis, fully internal, Universiteit van Amsterdam]. [details]
- Marsman, C. (2023). Regulation of human B cell differentiation. [Thesis, fully internal, Universiteit van Amsterdam]. [details]
- Steuten, J. (2023). Uncharted territories: Exploring the role of platelets, pO2 and atypical B cells in the regulation of immune balance. [Thesis, fully internal, Universiteit van Amsterdam]. [details]
- Verstegen, N. J. M. C. (2023). Going beyond your form: T-cell dependent B-cell fate determination. [Thesis, fully internal, Universiteit van Amsterdam]. [details]
2022
2021
- Berkhout, L. C. (2021). Dynamics of TNF during TNF inhibitor treatment. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
- de Waard, A. A. (2021). Tuning the show: Genetic engineering to unravel antigen presentation by the human leukocyte antigen class I. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
2020
2019
- Thielen, A. J. F. (2019). Regulation of complement activation on red blood cells. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
- van de Bovenkamp, F. S. (2019). The role of variable domain glycosylation of antibodies in immunity. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
2018
- Saris, A. (2018). Alloimmunization after platelet transfusion: Mechanisms, prevention and treatment. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
- Zaal, A. (2018). C5aR and TLR crosstalk: Regulatory effect of anaphylatoxin C5a on human dendritic cells. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
2017
- Marsman, G. (2017). Factor VII-activating protease: Unraveling the release and regulation of dead cell nuclear damps. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
- van Schie, K. A. J. (2017). Immunogenicity of therapeutic antibodies: Immunological mechanisms & clinical consequences. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
This list of publications is extracted from the UvA-Current Research Information System. Questions? Ask the library or the Pure staff of your faculty / institute. Log in to Pure to edit your publications. Log in to Personal Page Publication Selection tool to manage the visibility of your publications on this list. -
Nevenwerkzaamheden
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Sanquin Bloedvoorziening
Afdelingshoofd/manager afdeling immunopathologie
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Sanquin Bloedvoorziening
van Dam, K. P. J., Tas, S. W., Takkenberg, R. B., Bemelman, F. J., de Wit, J., Busch, M. H., Verstegen, N. J. M., van Ham, S. M., & T2B! immunity against SARS-CoV-2 study group (2023). Primary SARS-CoV-2 infection in patients with immune-mediated inflammatory diseases: long-term humoral immune responses and effects on disease activity. BMC Infectious Diseases, 23(1), Article 332.