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Dr. J.M. (Anneke) Alkemade

Faculty of Social and Behavioural Sciences
Programme group Brain and Cognition
Photographer: Anneke Alkemade

Visiting address
  • Nieuwe Achtergracht 129
Postal address
  • Postbus 15915
    1001 NK Amsterdam
Contact details
  • Profile

    My research efforts are focused on the functional anatomy of subcortical brain structures involved complex psychological processes including decision-making. The work is focused on the integration of microscopy approaches with 7 Tesla magnetic resonance imaging (MRI)  of the brain.

  • Publications

    2023

    • Alkemade, A., Großmann, R., Bazin, P-L., & Forstmann, B. U. (2023). Mixed methodology in human brain research: integrating MRI and histology. Brain Structure and Function, 228(6), 1399-1410. https://doi.org/10.1007/s00429-023-02675-2 [details]
    • Isherwood, S. J. S., Bazin, PL., Miletić, S., Stevenson, N. R., Trutti, A. C., Tse, D. H. Y., Heathcote, A., Matzke, D., Innes, R. J., Habli, S., Sokołowski, D. R., Alkemade, A., Håberg, A. K., & Forstmann, B. U. (2023). Investigating Intra-Individual Networks of Response Inhibition and Interference Resolution using 7T MRI. NeuroImage, 271, Article 119988. Advance online publication. https://doi.org/10.1016/j.neuroimage.2023.119988 [details]

    2022

    2021

    2020

    2019

    2018

    2017

    • Alkemade, A., de Hollander, G., Keuken, M. C., Schäfer, A., Ott, D. V. M., Schwarz, J., Weise, D., Kotz, S. A., & Forstmann, B. U. (2017). Comparison of T2* and QSM contrasts in Parkinson’s disease to visualize the STN with MRI. PLoS ONE, 12(4), Article e0176130. https://doi.org/10.1371/journal.pone.0176130 [details]
    • Forstmann, B. U., & Alkemade, A. (2017). The Neuroanatomy and Neurochemistry of Response Inhibition. In T. Egner (Ed.), The Wiley Handbook of Cognitive Control (pp. 274-291). Wiley Blackwell. https://doi.org/10.1002/9781118920497.ch16 [details]
    • Forstmann, B. U., de Hollander, G., van Maanen, L., Alkemade, A., & Keuken, M. C. (2017). Towards a mechanistic understanding of the human subcortex. Nature Reviews Neuroscience, 18(1), 57-65. Advance online publication. https://doi.org/10.1038/nrn.2016.163 [details]

    2016

    • ten Kulve, J. S., van Bloemendaal, L., Balesar, R., IJzerman, R. G., Swaab, D. F., Diamant, M., la Fleur, S. E., & Alkemade, A. (2016). Decreased Hypothalamic Glucagon-Like Peptide-1 Receptor Expression in Type 2 Diabetes Patients. Journal of clinical endocrinology and metabolism, 101(5), 2122-2129. https://doi.org/10.1210/jc.2015-3291 [details]

    2015

    2014

    • Alkemade, A., & Forstmann, B. U. (2014). Do we need to revise the tripartite subdivision hypothesis of the human subthalamic nucleus (STN)? NeuroImage, 95, 326-329. https://doi.org/10.1016/j.neuroimage.2014.03.010 [details]
    • Borgers, A. J., Koopman, K. E., Bisschop, P. H., Serlie, M. J., Swaab, D. F., Fliers, E., la Fleur, S. E., & Alkemade, A. (2014). Decreased serotonin transporter immunoreactivity in the human hypothalamic infundibular nucleus of overweight subjects. Frontiers in Neuroscience, 8, Article 106. https://doi.org/10.3389/fnins.2014.00106 [details]
    • Borgers, A. J., van den Born, B-JH., Alkemade, A., Eeftinck Schattenkerk, D. W., van Lieshout, J. J., Wesseling, K. H., Bisschop, P. H., & Westerhof, B. E. (2014). Determinants of vascular and cardiac baroreflex sensitivity values in a random population sample. Medical & Biological Engineering & Computing, 52(1), 65-73. Advance online publication. https://doi.org/10.1007/s11517-013-1111-0 [details]
    • Forstmann, B. U., Keuken, M. C., Schafer, A., Bazin, P-L., Alkemade, A., & Turner, R. (2014). Multi-modal ultra-high resolution structural 7-Tesla MRI data repository. Scientific Data, 1, Article 140050. https://doi.org/10.1038/sdata.2014.50 [details]
    • Girault, E. M., Guigas, B., Alkemade, A., Foppen, E., Ackermans, M. T., la Fleur, S. E., Fliers, E., & Kalsbeek, A. (2014). Chronic treatment with olanzapine increases adiposity by changing fuel substrate and causes desensitization of the acute metabolic side effects. Naunyn-Schmiedeberg's Archives of Pharmacology, 387(2), 185-195. https://doi.org/10.1007/s00210-013-0933-5 [details]

    2013

    • Alkemade, A. (2013). Subdivisions and anatomical borders of the subthalamic nucleus. The Journal of Neuroscience, 33(22), 9233-9234. https://doi.org/10.1523/JNEUROSCI.1266-13.2013 [details]
    • Alkemade, A., Keuken, M. C., & Forstmann, B. U. (2013). A perspective on terra incognita: uncovering the neuroanatomy of the human subcortex. Frontiers in Neuroanatomy, 7, Article 40. https://doi.org/10.3389/fnana.2013.00040 [details]
    • Borgers, A. J., Alkemade, A., van de Giessen, E. M., Drent, M. L., Booij, J., Bisschop, P. H., & Fliers, E. (2013). Imaging of serotonin transporters with [123I]FP-CIT SPECT in the human hypothalamus. EJNMMI Research, 3, 34. Article 34. https://doi.org/10.1186/2191-219X-1-34 [details]
    • Borgers, A. J., Fliers, E., Siljee, J. E., Swaab, D. F., Van Someren, E. J. W., Bisschop, P. H., & Alkemade, A. (2013). Arginine vasopressin immunoreactivity is decreased in the hypothalamic suprachiasmatic nucleus of subjects with suprasellar tumors. Brain Pathology, 23(4), 440-444. https://doi.org/10.1111/bpa.12016 [details]
    • Mittag, J., Lyons, D. J., Sällström, J., Vujoviv, M., Dudazy-Gralla, S., Warner, A., Wallis, K., Alkemade, A., Nordström, K., Monyer, H., Broberger, C., Arner, A., & Vennström, B. (2013). Thyroid hormone is required for hypothalamic neurons regulating cardiovascular functions. The journal of clinical investigation, 123(1), 509-516. https://doi.org/10.1172/JCI65252 [details]
    • Siljee, J. E., Unmehopa, U. A., Kalsbeek, A., Swaab, D. F., Fliers, E., & Alkemade, A. (2013). Melanocortin 4 receptor distribution in the human hypothalamus. European journal of endocrinology, 168(3), 361-369. https://doi.org/10.1530/EJE-12-0750 [details]

    2005

    • Alkemade, A., Ummehopa, U. A., Wiersinga, W. M., Swaab, D. F., & Fliers, E. (2005). Glucocorticoids decrease thyrotropin-releasing hormone messenger ribonucleic acid expression in the paraventricular nucleus of the human hypothalamus. Journal of clinical endocrinology and metabolism, 90(1), 323-327. https://doi.org/10.1210/jc.2004-1430 [details]

    2016

    2005

    • Alkemade, J. M. (2005). Central components of the human hypothalamus-pituitary-thyroid axis and their role in nonthyroidal illness. [Thesis, fully internal, Universiteit van Amsterdam]. [details]

    2023

    • Bazin, P. L. E. A., Forstmann, B. U., Alkemade, J. M., Miletić, S. & Isherwood, S. J. S. (8-7-2023). AHEAD quantitative MRI templates (MNI2009b). Universiteit van Amsterdam. https://doi.org/10.21942/uva.19646364.v3
    • Isherwood, S. J. S., Bazin, P. L. E. A., Miletić, S., Stevenson, N. R., Trutti, A., H. Y. Tse, D., Heathcote, A., Matzke, D., Habli, S., Sokołowski, D. R., Alkemade, A., Håberg, A., Forstmann, B. & Innes, R. (8-6-2023). Investigating Intra-Individual Networks of Response Inhibition and Interference Resolution using 7T MRI data. Universiteit van Amsterdam. https://doi.org/10.21942/uva.22240393.v1

    2022

    2021

    • Keuken, M., Liebrand, L., Bazin, P., Alkemade, A., van Berendonk, N., Groot, J., Isherwood, S., Kemp, S., Lute, N., Mulder, M., Trutti, A., Caan, M. W. A. & Forstmann, B. (28-10-2021). A high-resolution multi-shell 3T diffusion magnetic resonance imaging dataset as part of the Amsterdam Ultra-high field adult lifespan database (AHEAD) - dataset. Universiteit van Amsterdam. https://doi.org/10.21942/uva.16884703.v1
    • Alkemade, J. M., Mulder, M. J., Trutti, A. C. & Forstmann, B. U. (16-3-2021). Manual Delineation approaches for direct imaging of the subcortex. Universiteit van Amsterdam. https://doi.org/10.21942/uva.14216504.v2
    • Forstmann, B., Keuken, M., Schafer, A., Bazin, P.-L., Alkemade, A. & Turner, R. (2021). Data from: Multi-modal ultra-high resolution structural 7-Tesla MRI data repository. DRYAD. https://doi.org/10.5061/dryad.fb41s

    2020

    • Alkemade, J. M., Pine, K., Kirilina, E., Keuken, M., Mulder, M., Balesar, R., Groot, J., L. A. W. Bleys, R., Trampel, R., Weiskopf, N., Herrler, A., Möller, H., Bazin, P. & Forstmann, B. (14-9-2020). 7 Tesla MRI followed by histological 3D reconstructions in whole-brain specimens. Universiteit van Amsterdam. https://doi.org/10.21942/uva.12496853.v1
    • Bazin, P. L. E. A., Forstmann, B. & Alkemade, A. (14-5-2020). AHEAD template. Universiteit van Amsterdam. https://doi.org/10.21942/uva.12301106.v2

    2019

    • Bazin, P. L. E. A., Alkemade, A., van der Zwaag, W., Caan, M. W. A., Mulder, M. & Forstmann, B. (5-4-2019). Raw measurements for the statistics. Universiteit van Amsterdam. https://doi.org/10.21942/uva.7952270.v1

    2018

    • Alkemade, A., Kotz, S. A., Ott, D. V. M., Keuken, M. C., Schwarz, J., Weise, D., Schäfer, A., Forstmann, B. U. & de Hollander, G. (2018). Data from: Comparison of T2*-weighted and QSM contrasts in Parkinson's disease to visualize the STN with MRI. DRYAD. https://doi.org/10.5061/dryad.t7kp7
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  • Ancillary activities
    • No ancillary activities