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Silhouet of a head with a missing puzzle piece
Image: Pxhere

MODEM: studying Mechanisms Of DEMentia

The consortium 'Fundamental research' has been honoured, in which several parties work together to answer major questions within research into dementia, under the name MODEM (Mechanisms Of DEMentia). The consortium receives €5.9 million. 

Led by professor of neurobiology and board member CNCR and Amsterdam Neuroscience Guus Smit from the Amsterdam UMC, the neuroscientists will investigate the disease mechanisms underlying dementia, such as Alzheimer's disease (AD), fronto-temporal dementia (FTD), and vascular dementia. The causes of this are still largely unknown, and there are no effective treatments yet. By better understanding the disease mechanisms, we learn more about the development of dementia, the protection against it, and this gives opportunities to develop new therapies. At SILS-UvA two PhD positions will contribute to the consortium efforts.

Collaboration partners

Not only do research institutes participate, but also educational institutions, care providers and the business community. As a result, new knowledge can also quickly reach the workplace and companies. The four awarded consortia will start before the end of the year, and a fifth National Dementia Strategy consortium application is still pending.

National dementia strategy

The Dementia Research Program is part of the National Dementia Strategy 2021-2030 of the Ministry of Health, Welfare and Sport (VWS). It fulfils an important part of VWS mission IV: By 2030, the quality of life of people with dementia will have increased by 25%. To this end, a coalition of many public and private partners drew up the Knowledge and Innovation Agenda 2020-2023, together with the Top Sector Life Sciences & Health (LSH).

Affiliated research groups