Dr C.J.M. de Vries (1960) has been named Professor of Medical Cell Biochemistry at the Faculty of Medicine of the University of Amsterdam (AMC-UvA).
Carlie de Vries uses her research to gain detailed insight into the molecular processes involved in the initiation and progression of atherosclerosis. Atherosclerosis is a condition affecting the arterial vessel wall that can ultimately lead to obstruction of normal blood flow resulting in a heart attack or stroke. Through her molecular biological research, De Vries is able to identify genes that have a key regulatory function in atherosclerosis. The resulting insights are used towards early patient diagnosis and to develop innovative treatment strategies. De Vries works in close collaboration with cardiologists at the AMC, thus ensuring maximum integration with clinical practice and the translation of new fundamental knowledge into practical applications. Recently, De Vries received a research subsidy totalling five million euros from Biomedical Materials to conduct basic scientific vascular research and to collaborate with three small companies and TU Delft on the development of a safer stent (a small tubular device used to keep an artery open after angioplasty).
De Vries has been working in the Department of Medical Biochemistry at the AMC since 1994, first as a postdoc and, since 2000, as a full staff member. Before this she worked at the University of California, San Francisco, and the Hubrecht Institute for Developmental Biology and Stem Cell Research in Utrecht, as part of a post-doc fellowship from the Netherlands Organisation for Scientific Research (NWO). She has been involved in the ‘Molecular Cardiology Programme' supported by the Netherlands Heart Association since 1994; since 2002 as an Established Investigator.