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Dr. ir. W.C. (Wim) de Leeuw

Faculty of Science
Swammerdam Institute for Life Sciences
Visiting address
  • Science Park 904
  • Room number: C2.201
Postal address
  • Postbus 1212
    1000 BE Amsterdam
Contact details
  • Publications

    2017

    • Rauwerda, H., Pagano, J. F. B., de Leeuw, W. C., Ensink, W., Nehrdich, U., de Jong, M., Jonker, M., Spaink, H. P., & Breit, T. M. (2017). Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. BMC Genomics, 18, [287]. https://doi.org/10.1186/s12864-017-3672-z [details]
      • Related datasets
        • Pagano, J., Ensink, W., Breit, T. M., de Leeuw, W., Rauwerda, H., Jonker, M., Spaink, H. P., de Jong, M. & Nehrdich, U. (11-4-2017). Additional file 11: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d2.v1
        • Jonker, M., Nehrdich, U., Spaink, H. P., de Jong, M., Ensink, W., de Leeuw, W., Rauwerda, H., Breit, T. M. & Pagano, J. (11-4-2017). Additional file 18: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d9.v1
        • de Jong, M., Ensink, W., Jonker, M., Breit, T. M., Spaink, H. P., de Leeuw, W., Rauwerda, H., Nehrdich, U. & Pagano, J. (11-4-2017). Additional file 17: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d8.v1
        • Jonker, M., de Leeuw, W., Breit, T. M., de Jong, M., Nehrdich, U., Rauwerda, H., Spaink, H. P., Pagano, J. & Ensink, W. (11-4-2017). Additional file 9: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d18.v1
        • Pagano, J., Nehrdich, U., de Jong, M., Breit, T. M., Rauwerda, H., Jonker, M., Ensink, W., Spaink, H. P. & de Leeuw, W. (11-4-2017). Additional file 16: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d7.v1
        • Pagano, J., Breit, T. M., Spaink, H. P., de Jong, M., Rauwerda, H., Nehrdich, U., Ensink, W., Jonker, M. & de Leeuw, W. (11-4-2017). Additional file 8: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d17.v1
        • Ensink, W., Breit, T. M., Spaink, H. P., Rauwerda, H., Jonker, M., Pagano, J., Nehrdich, U., de Leeuw, W. & de Jong, M. (11-4-2017). Additional file 15: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d6.v1
        • Ensink, W., Jonker, M., Spaink, H. P., Breit, T. M., Nehrdich, U., de Jong, M., de Leeuw, W., Rauwerda, H. & Pagano, J. (11-4-2017). Additional file 7: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d16.v1
        • de Jong, M., Ensink, W., de Leeuw, W., Rauwerda, H., Nehrdich, U., Spaink, H. P., Breit, T. M., Pagano, J. & Jonker, M. (11-4-2017). Additional file 14: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d5.v1
        • Ensink, W., Pagano, J., de Jong, M., Rauwerda, H., Nehrdich, U., Breit, T. M., Spaink, H. P., Jonker, M. & de Leeuw, W. (11-4-2017). Additional file 6: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d15.v1
        • Jonker, M., de Leeuw, W., Pagano, J., Spaink, H. P., de Jong, M., Ensink, W., Breit, T. M., Rauwerda, H. & Nehrdich, U. (11-4-2017). Additional file 13: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d4.v1
        • Ensink, W., Spaink, H. P., de Leeuw, W., Nehrdich, U., de Jong, M., Jonker, M., Breit, T. M., Rauwerda, H. & Pagano, J. (11-4-2017). Additional file 5: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d14.v1
        • Nehrdich, U., Jonker, M., Breit, T. M., Ensink, W., de Leeuw, W., Pagano, J., Rauwerda, H., de Jong, M. & Spaink, H. P. (11-4-2017). Additional file 12: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d3.v1
        • Jonker, M., Ensink, W., Breit, T. M., Nehrdich, U., de Jong, M., de Leeuw, W., Spaink, H. P., Pagano, J. & Rauwerda, H. (11-4-2017). Additional file 4: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d13.v1
        • Breit, T. M., Rauwerda, H., de Leeuw, W., Ensink, W., Spaink, H. P., Pagano, J., Nehrdich, U., Jonker, M. & de Jong, M. (11-4-2017). Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003.v1
        • Spaink, H. P., Ensink, W., Rauwerda, H., Pagano, J., de Jong, M., de Leeuw, W., Jonker, M., Nehrdich, U. & Breit, T. M. (11-4-2017). Additional file 3: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d12.v1
        • Nehrdich, U., Rauwerda, H., Breit, T. M., Jonker, M., Spaink, H. P., Pagano, J., de Leeuw, W., de Jong, M. & Ensink, W. (11-4-2017). Additional file 10: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d1.v1
        • de Jong, M., Breit, T. M., Spaink, H. P., de Leeuw, W., Pagano, J., Rauwerda, H., Jonker, M., Ensink, W. & Nehrdich, U. (11-4-2017). Additional file 2: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d11.v1
        • Jonker, M., Nehrdich, U., Breit, T. M., Spaink, H. P., de Jong, M., de Leeuw, W., Ensink, W., Pagano, J. & Rauwerda, H. (11-4-2017). Additional file 1: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d10.v1
    • van Hagen, M., Piebes, D. G. E., de Leeuw, W. C., Vuist, I. M., van Roon-Mom, W. M. C., Moerland, P. D., & Verschure, P. J. (2017). The dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell model. BMC Genomics, 18(373), [373]. https://doi.org/10.1186/s12864-017-3745-z [details]

    2016

    2015

    2012

    • Marinković, M., de Leeuw, W. C., Ensink, W. A., de Jong, M., Breit, T. M., Admiraal, W., Kraak, M. H. S., & Jonker, M. J. (2012). Gene expression patterns and life cycle responses of toxicant-exposed chironomids. Environmental Science and Technology, 46(22), 12679-12686. https://doi.org/10.1021/es3033617 [details]
    • Marinković, M., de Leeuw, W. C., de Jong, M., Kraak, M. H. S., Admiraal, W., Breit, T. M., & Jonker, M. J. (2012). Combining next-generation sequencing and microarray technology into a transcriptomics approach for the non-model organism Chironomus riparius. PLoS ONE, 7(10), e48096. https://doi.org/10.1371/journal.pone.0048096 [details]

    2010

    2009

    2008

    2007

    • Rauwerda, H., de Leeuw, W. C., Adriaanse, J., Bouwhuis, M., van der Vet, P., & Breit, T. M. (2007). The role of e-BioLabs in a life sciences collaborative working environment. In Proceedings Conference e-Challenges [details]

    2003

    • Manders, E. M. M., Visser, A. E., Koppen, A., de Leeuw, W. C., van Liere, R., Brakenhoff, G. J., & van Driel, R. (2003). Four-dimensional imaging of chromatin dynamics during the assembly of the interphase nucleus. Chromosome Research, 11, 537-547. https://doi.org/10.1023/A:1024995215340 [details]

    2014

    • Jonker, M. J., de Leeuw, W. C., Marinković, M., Wittink, F. R. A., Rauwerda, H., Bruning, O., Ensink, W. A., Fluit, A. C., Boel, C. H., de Jong, M., & Breit, T. M. (2014). Absence/presence calling in microarray-based CGH experiments with non-model organisms. Nucleic Acids Research, 42(11), e94. https://doi.org/10.1093/nar/gku343 [details]

    2012

    • Marinkovic, M., de Leeuw, W. C., de Jong, M., Admiraal, W., Breit, T. M., Kraak, M. H. S., & Jonker, M. J. (2012). Sequencing the Chironomus riparius transcriptome to compare the sensitivity of gene expression and life-cycle endpoints to toxicant exposure.. Abstract from 6th SETAC World Congress/SETAC Europe 22nd Annual Meeting, Berlin, Germany, May 2012. http://berlin.setac.eu/embed/Berlin/ET_extended_abstracts_Part1.pdf

    2020

    • Pagano, J. F. B., Locati, M. D., Ensink, W. A., van Olst, M., van Leeuwen, S., de Leeuw, W. C., Nehrdich, U., Spaink, H. P., Rauwerda, H., Jonker, M. J., Dekker, R. J., & Breit, T. M. (2020). Maternal- and Somatic-type snoRNA Expression and Processing in Zebrafish Development. BioRxiv. https://doi.org/10.1101/858936 [details]

    2019

    2017

    • Jonker, M., Nehrdich, U., Spaink, H. P., de Jong, M., Ensink, W., de Leeuw, W., Rauwerda, H., Breit, T. M. & Pagano, J. (11-4-2017). Additional file 18: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d9.v1
    • Ensink, W., Breit, T. M., Spaink, H. P., Rauwerda, H., Jonker, M., Pagano, J., Nehrdich, U., de Leeuw, W. & de Jong, M. (11-4-2017). Additional file 15: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d6.v1
    • Breit, T. M., Rauwerda, H., de Leeuw, W., Ensink, W., Spaink, H. P., Pagano, J., Nehrdich, U., Jonker, M. & de Jong, M. (11-4-2017). Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003.v1
    • Jonker, M., de Leeuw, W., Breit, T. M., de Jong, M., Nehrdich, U., Rauwerda, H., Spaink, H. P., Pagano, J. & Ensink, W. (11-4-2017). Additional file 9: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d18.v1
    • Nehrdich, U., Jonker, M., Breit, T. M., Ensink, W., de Leeuw, W., Pagano, J., Rauwerda, H., de Jong, M. & Spaink, H. P. (11-4-2017). Additional file 12: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d3.v1
    • Pagano, J., Breit, T. M., Spaink, H. P., de Jong, M., Rauwerda, H., Nehrdich, U., Ensink, W., Jonker, M. & de Leeuw, W. (11-4-2017). Additional file 8: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d17.v1
    • Pagano, J., Ensink, W., Breit, T. M., de Leeuw, W., Rauwerda, H., Jonker, M., Spaink, H. P., de Jong, M. & Nehrdich, U. (11-4-2017). Additional file 11: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d2.v1
    • Nehrdich, U., Rauwerda, H., Breit, T. M., Jonker, M., Spaink, H. P., Pagano, J., de Leeuw, W., de Jong, M. & Ensink, W. (11-4-2017). Additional file 10: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d1.v1
    • Pagano, J., Nehrdich, U., de Jong, M., Breit, T. M., Rauwerda, H., Jonker, M., Ensink, W., Spaink, H. P. & de Leeuw, W. (11-4-2017). Additional file 16: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d7.v1
    • Ensink, W., Spaink, H. P., de Leeuw, W., Nehrdich, U., de Jong, M., Jonker, M., Breit, T. M., Rauwerda, H. & Pagano, J. (11-4-2017). Additional file 5: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d14.v1
    • Ensink, W., Jonker, M., Spaink, H. P., Breit, T. M., Nehrdich, U., de Jong, M., de Leeuw, W., Rauwerda, H. & Pagano, J. (11-4-2017). Additional file 7: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d16.v1
    • Jonker, M., Nehrdich, U., Breit, T. M., Spaink, H. P., de Jong, M., de Leeuw, W., Ensink, W., Pagano, J. & Rauwerda, H. (11-4-2017). Additional file 1: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d10.v1
    • Ensink, W., Pagano, J., de Jong, M., Rauwerda, H., Nehrdich, U., Breit, T. M., Spaink, H. P., Jonker, M. & de Leeuw, W. (11-4-2017). Additional file 6: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d15.v1
    • Jonker, M., Ensink, W., Breit, T. M., Nehrdich, U., de Jong, M., de Leeuw, W., Spaink, H. P., Pagano, J. & Rauwerda, H. (11-4-2017). Additional file 4: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d13.v1
    • de Jong, M., Breit, T. M., Spaink, H. P., de Leeuw, W., Pagano, J., Rauwerda, H., Jonker, M., Ensink, W. & Nehrdich, U. (11-4-2017). Additional file 2: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d11.v1
    • de Jong, M., Ensink, W., Jonker, M., Breit, T. M., Spaink, H. P., de Leeuw, W., Rauwerda, H., Nehrdich, U. & Pagano, J. (11-4-2017). Additional file 17: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d8.v1
    • Spaink, H. P., Ensink, W., Rauwerda, H., Pagano, J., de Jong, M., de Leeuw, W., Jonker, M., Nehrdich, U. & Breit, T. M. (11-4-2017). Additional file 3: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d12.v1
    • de Jong, M., Ensink, W., de Leeuw, W., Rauwerda, H., Nehrdich, U., Spaink, H. P., Breit, T. M., Pagano, J. & Jonker, M. (11-4-2017). Additional file 14: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d5.v1
    • Jonker, M., de Leeuw, W., Pagano, J., Spaink, H. P., de Jong, M., Ensink, W., Breit, T. M., Rauwerda, H. & Nehrdich, U. (11-4-2017). Additional file 13: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. figshare Academic Research System. https://doi.org/10.6084/m9.figshare.c.3740003_d4.v1
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